Background: Infection prevention and control involve health care practitioners, who are saddled with the duty of ensuring implementation of standard preventive measures to prevent healthcare associated infections.
Objectives: To assess the knowledge and predictors of implementation of standard precautions for infection prevention and control among health care practitioners (HCPs).
Material And Method: A questionnaire-based cross-sectional design was employed in assessing HCPs in Uganda in from April - October 2023.
Actomyosin machinery endows cells with contractility at a single-cell level. However, within a monolayer, cells can be contractile or extensile based on the direction of pushing or pulling forces exerted by their neighbours or on the substrate. It has been shown that a monolayer of fibroblasts behaves as a contractile system while epithelial or neural progentior monolayers behave as an extensile system.
View Article and Find Full Text PDFThe directed migration of cell collectives is essential in various physiological processes, such as epiboly, intestinal epithelial turnover, and convergent extension during morphogenesis as well as during pathological events like wound healing and cancer metastasis. Collective cell migration leads to the emergence of coordinated movements over multiple cells. Our current understanding emphasizes that these movements are mainly driven by large-scale transmission of signals through adherens junctions.
View Article and Find Full Text PDFUnlabelled: Transcatheter closure of atrial septal defects (ASDs) using nickel titanium Naval Ordnance Laboratory (Nitinol)-containing devices (Amplatzer, AGA Medical, Golden Valley, Minnetosa) is being widely practiced. Controversies still exist regarding the release of nickel from these devices and the allergy and other ill effects of nickel and also the duration of antiplatelet therapy to aid endothelization of the device.
Objective: To study the nickel levels in patients who underwent ASD closure with platinum-coated Nitinol-containing Amplatzer septal occluder.
Cytoskeleton (Hoboken)
February 2019
Here, we have reported that keratinocytes respond to the microflow-induced shear stress both at the collective and individual cell level. Using a microfluidic setup, we categorically showed that low shear stress of magnitude 0.06 dyne/cm could induce morphological variation and cytoskeletal reorganization in keratinocyte, whereas higher shear stress (6 dyne/cm ) resulted in cellular disruption.
View Article and Find Full Text PDFThe aim of this study was to compare the remineralization potential of three different dentifrices using Raman spectroscopy and confocal laser scanning microscopy (CLSM). Totally, 30 extracted intact impacted third molar teeth were selected and the crown of each tooth in a group was separated from the root and longitudinally sectioned into four parts with each section under a subgroup, of which one section was an untreated section, the second and the third sections were demineralized in a demineralizing solution, and the third section was remineralized after demineralization. The teeth in the three groups were demineralized for 4 days and then treated with 0.
View Article and Find Full Text PDFIntroduction: Cervical cancer-related deaths among women in India are often due to late diagnosis of disease. Knowledge about disease and early screening is the most effective measure for cervical cancer prevention. Lack of awareness, negative attitude, and poor practice about cervical cancer and screening are the major causes to increase the incidence of disease.
View Article and Find Full Text PDFThe shaping of a multicellular body and repair of adult tissues require fine--tuning of cell adhesion, cell mechanics, and intercellular transmission of mechanical load. Adherens junctions (AJs) are the major intercellular junctions by which cells sense and exert mechanical force on each other. However, how AJs adapt to mechanical stress and how this adaptation contributes to cell-cell cohesion and eventually to tissue-scale dynamics and mechanics remains largely unknown.
View Article and Find Full Text PDFIntroduction: is a rich source for phenols and the wood, leaves, and flowers of the plant are used as medicinal agents in traditional medicine. Peptic ulcer is a major disease of gastrointestinal tract, affecting nearly 40 lac people each year worldwide and affects 10% of world population with different aetiologies. consists of phenols and flavonoids, tannins which have potential antioxidant and cytoprotective activity.
View Article and Find Full Text PDFIsolated Unilateral hypoplasia or agenesis of a branch of pulmonary artery is very rare. It is usually seen associated with congenital heart diseases such as tetralogy of Fallot, atrial septal defect, coarctation of the aorta, right aortic arch, truncus arteriosus, patent ductus arteriosus and pulmonary atresia. It occurs as a result of lack of embryological development of either the left or right sixth aortic arch and has been found to present itself with various clinical manifestations as during childhood it presents as contralateral pulmonary hypertension and in adults as haemoptysis.
View Article and Find Full Text PDFSuccess of bone tissue engineering (BTE) relies on the osteogenic microarchitecture of the biopolymeric scaffold and appropriate spatiotemporal distribution of therapeutic molecules (growth factors and drugs) inside it. However, the existing technologies have failed to address both the issues together. Keeping this perspective in mind, we have developed a novel three-dimensional (3D) implant prototype by stacking hexagonal close packed (HCP) layers of calcium alginate beads.
View Article and Find Full Text PDFOf the world's 1.2 billion adolescents (10-19 years), India is home to the largest number globally, about 243 million. However not much is known about the health of young adolescent girls (11-14 years) in India who enter puberty with substantial nutritional and health deficits.
View Article and Find Full Text PDFZr complexes of the type [Me Si{(NR)(6-{2-(diethylboryl)phenyl}pyridyl-2-yl-N)}ZrCl ⋅thf] (R=tBu (4), adamantyl (7 a); thf=tetrahydrofuran), [Me Si{(NAd)(6-{2-(diphenylboryl)phenyl}pyridyl-2-yl-N)}ZrCl ] (Ad=adamantyl (7 b)), the nonbridged half-titanocene complexes of the type [(N-{6-(2-diethylborylphenyl)pyrid-2-yl}-NR)Cp'TiCl ] (R=Me, Cp'=C H (12), Cp'=C Me (13)), and the titanium(IV)-based metallocene-type complex [bis{N-(6-{2-(diethylboryl)phenyl}pyrid-2-yl)NMe}TiCl ] (14) have been synthesized. The structures of complexes 7 b, 12, and 13 were determined by single-crystal X-ray diffraction analysis. In solution, complex 4 slowly rearranges to [Me Si{(N-tBu)(6-{2-(diethylboryl)phenyl}pyridyl-2-yl-N)} Zr] (4 a), the structure of which was unambiguously confirmed by single-crystal X-ray crystallography.
View Article and Find Full Text PDFExtramedullary plasmacytoma of tonsil is rare. Even though biopsy is necessary for final diagnosis, fine-needle aspiration cytology (FNAC) can provide useful information in the management of such cases. We report a case of plasmacytoma of tonsil diagnosed by FNAC in a 43-year-old man who presented with a swelling in the right tonsillar area.
View Article and Find Full Text PDFForeign body ear is a common problem. When it is impacted it can tax the resorces of each of us. An attempt is made in this paper to make a customable foreign body removal hook using a lumbar puncture needle.
View Article and Find Full Text PDFWe report a female infant with features suggestive of Oral Facial Digital Syndrome (OFDS) Type I and associated cerebellar anomalies with Dandy-Walker malformation which suggest OFDS Type VI. The phenotypic overlap in this child OFDS type I and TypeVI raises the question as to whether they represent separate genetic entities. This pattern of abnormalities appears to be unique.
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