Metal and heteroatoms co-doped fluorescent carbon dots for highly selective and sensitive detection of Mg ions in aqueous media: Applications in test strips, pharmaceutical, real samples and bioimaging.

In this study, we successfully synthesized fluorescent carbon dots (CDs) through a one-pot hydrothermal method, utilizing tartaric acid, cysteine, and nickel chloride as precursors. This approach allowed for the incorporation of metal ion (nickel) as well as nitrogen and sulfur heteroatoms into the carbon dot structure, resulting in nickel-doped, nitrogen, and sulfur-co-doped CDs (Ni/NS-CDs). A comprehensive characterization of the Ni/NS-CDs was conducted using FT-IR, XRD, Raman, XPS, and HR-TEM analysis confirmed the successful doping of nickel, nitrogen, and sulfur into the Ni/NS-CDs.

A Review on Recent Development of Phenothiazine-Based Chromogenic and Fluorogenic Sensors for the Detection of Cations, Anions, and Neutral Analytes.

This review provides an in-depth examination of recent progress in the development of chemosensors, with a particular emphasis on colorimetric and fluorescent probes. It systematically explores various sensing mechanisms, including metal-to-ligand charge transfer (MLCT), ligand-to-metal charge transfer (LMCT), photoinduced electron transfer (PET), intramolecular charge transfer (ICT), and fluorescence resonance energy transfer (FRET), and elucidates the mechanism of action for cation and anion chemosensors. Special attention is given to phenothiazine-based fluorescence probes, highlighting their exceptional sensitivity and rapid detection abilities for a broad spectrum of analytes, including cations, anions, and small molecules.

A thiazole-based colorimetric and photoluminescent chemosensors for As ions detection: Density functional theory, test strips, real samples, and bioimaging applications.

A Schiff-base Ethyl (E)-2-(3-((2-carbamothioylhydrazono)methyl)-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate (TZTS) dual functional colorimetric and photoluminescent chemosensor which includes thiazole and thiosemicarbazide has been synthesized to detect arsenic (As) ions selectively in DMSO: HO (7:3, v/v) solvent system. The molecular structure of the probe was characterized via FT-IR, H, and C NMR & HRMS analysis. Interestingly, the probe exhibits a remarkable and specific colorimetric and photoluminescence response to As ions when exposed to various metal cations.

Phenothiazine appended thiophene derivative: a trilateral approach to copper ion detection in living cells and aqueous samples.

This research paper unveils a fluorescent probe (PTZ-SCN) engineered for the specific detection of Cu, featuring a 10-ethyl-10-phenothiazine-3-carbaldehyde and 2-(thiophen-2-yl) acetonitrile moiety. The fluorescence sensing behavior of PTZ-SCN towards various metal cations was scrutinized in CHCN : HEPES (9 : 1) buffer aqueous solution. The UV absorbance of PTZ-SCN displayed a distinct red shift in the presence of Cu cations, whereas other metal cations did not cause any interference.

Functionalized 2-Hydrazinobenzothiazole with Bithiophene as a Colorimetric Sensor for Lethal Cyanide Ions and Its Application in Food Samples.

A newly synthesized Schiff's base 2-(2-([2,2'-bithiophen]-5-ylmethylene)hydrazinyl)benzothiazole () was obtained from the condensation reaction between 2-hydrazinobenzothiazole and 2,2-bithiophene-5-carboxaldehyde. The prepared probe was subjected to a confirmation of the structural arrangement through NMR, FTIR, ESI-HRMS, and single-crystal XRD spectral analysis. The colorimetric sensor showed selectivity and sensitivity toward the cyanide (CN) ion over other common anions such as ClO, Cl, Br, F, I, NO, OH, HSO, and HPO in a partial aqueous system CHCN/HO (8:2, v/v).

Pro- and Anti-Inflammatory Cytokine Expression Levels in Macrophages; An Approach to Develop Indazolpyridin-Methanones as a Novel Inflammation Medication.

Background: Macrophages play a serious part in the instigation, upkeep, and resolution of inflammation. They are activated or deactivated during inflammation progression. Activation signals include cytokines (IF-γ, granulocyte-monocyte colonystimulating factor (GM-CSF), and TNF-α), extracellular matrix proteins, and other chemical mediators.

Enhanced solubility of guanosine by inclusion complexes with cyclodextrin derivatives: Preparation, characterization, and evaluation.

This study improves the water solubility and cellular uptake of guanosine (GuN) through an inclusion complexation with cyclodextrin derivatives (CDs), namely β-cyclodextrin (β-CD), hydroxypropyl-β-cyclodextrin (HP-β-CD), and sulfobutyl ether-β-cyclodextrin (SBE-β-CD). Inclusion complexes of GuN and CDs are synthesized in a 1:1 stoichiometric ratio with binding constants calculated using the Benesi-Hildebrand method. Characterizations of the prepared solid complexes using FTIR, XRD, TGA-DSC, and SEM indicate that GuN is found inside the cavity of the CDs.