Cell cycle dependent phosphatase activity in Bacillus subtilis.

In Bacillus subtilis there is evidence that the replication origin of the DNA molecule is attached to the cytoplasmic membrane, and that this attachment is essential for the initiation of replication. We have previously shown that attachment of DNA to the membrane is cyclic and that DNA becomes attached to the cytoplasmic membrane at the beginning of replication and is subsequently released. We have also shown that membrane protein phosphorylation is associated with the initiation of DNA replication in B.