Publications by authors named "Naomi Platt"
Background: The protection of fourth dose mRNA vaccination against SARS-CoV-2 is relevant to current global policy decisions regarding ongoing booster roll-out. We aimed to estimate the effect of fourth dose vaccination, prior infection, and duration of PCR positivity in a highly-vaccinated and largely prior-COVID-19 infected cohort of UK healthcare workers.
Methods: Participants underwent fortnightly PCR and regular antibody testing for SARS-CoV-2 and completed symptoms questionnaires.
Article Synopsis
- The SIREN study began in June 2020, focusing on PCR testing and sequencing in UK healthcare workers to monitor SARS-CoV-2 infections and reinfections.
- It identified a rise in infections and reinfections, as well as the emergence of Omicron subvariant waves, aligning with national data.
- SIREN's approach serves as an effective method for ongoing variant surveillance.
With the exception of target site mutations, insecticide resistance mechanisms in the principle malaria vector Anopheles gambiae, remains largely uncharacterized in Burkina Faso. Here we detected high prevalence of resistance in Vallée du Kou (VK) to pyrethroids, DDT and dieldrin, moderate level for carbamates and full susceptibility to organophosphates. High frequencies of L1014F kdr (75%) and Rdl (87%) mutations were observed showing strong correlation with pyrethroids/DDT and dieldrin resistance.
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