Publications by authors named "Naomi Miura"
Article Synopsis
- Ustekinumab, an anti-interleukin-12/23 monoclonal antibody, was studied for its safety and effectiveness in treating Crohn's disease in Japan, with data collected from May 2017 to June 2020 across 91 medical centers.
- The study involved 341 patients, showing low rates of adverse drug reactions (5.3%) and serious adverse reactions (2.1%), with worsening of Crohn's disease being the most common issue.
- At 8 weeks, 40% of patients showed clinical response and 48.5% achieved clinical remission, along with significant improvement in disease activity scores; overall, the therapy was deemed effective and safe without new safety concerns.
Usually, fetal asphyxia/demise because of umbilical cord entanglement and secondary cord occlusion is a unique characteristic of monoamniotic twin pregnancies. We present here a rare case of fetal asphyxia due to cord entanglement in a monochorionic diamniotic twin pregnancy complicated by 2nd-trimester single intrauterine demise. In this case, there was no amniocentesis or any other invasive intrauterine procedure performed during pregnancy.
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