Repeatability and reproducibility of multiparametric magnetic resonance imaging of the liver.

As the burden of liver disease reaches epidemic levels, there is a high unmet medical need to develop robust, accurate and reproducible non-invasive methods to quantify liver tissue characteristics for use in clinical development and ultimately in clinical practice. This prospective cross-sectional study systematically examines the repeatability and reproducibility of iron-corrected T1 (cT1), T2*, and hepatic proton density fat fraction (PDFF) quantification with multiparametric MRI across different field strengths, scanner manufacturers and models. 61 adult participants with mixed liver disease aetiology and those without any history of liver disease underwent multiparametric MRI on combinations of 5 scanner models from two manufacturers (Siemens and Philips) at different field strengths (1.

Vitamin D intake in Australian adults and the modeled effects of milk and breakfast cereal fortification.

Objective: Vitamin D intake from foods or supplements is a safe and attractive means to improve vitamin D status of populations. The aim of this study was to help identify population subgroups that would benefit most from efforts to increase intake. To do so, we investigated which personal characteristics are associated with vitamin D intake in an Australian population and modeled possible effects of expanded food fortification practices.

Sun protection and vitamin D status in an Australian subtropical community.

Objective: Claims have been made that sun protection may negatively affect vitamin D status, but very few data are available about whether this applies to people in uncontrolled settings.

Method: In 1996 we measured 25(OH)-vitamin D concentrations in 1113 adults in Nambour, a subtropical community, who reported their concurrent sun protection behaviours in a skin cancer prevention trial. Estimates were adjusted for time outdoors, vitamin D intake and other factors known to affect vitamin D status.