Publications by authors named "Naomi Hassan Kahtan Alyafei"
Article Synopsis
- Breast cancer becomes invasive when carcinoma cells break through the basement membrane (BM), a barrier that separates the tumor from surrounding tissue.
- Researchers created a 3D model to study how multiple cancer cells invade the BM collectively, finding that they use a combination of proteases and mechanical forces without relying on invadopodia.
- The study reveals that the invasion process involves both the expansion of cell volume, which stretches the BM, and local forces that help breach it, highlighting a key mechanism in cancer metastasis.
