Publications by authors named "Naomi Alyafei"
Article Synopsis
- Breast cancer becomes invasive when carcinoma cells break through the basement membrane (BM), a barrier that separates the tumor from surrounding tissue.
- Researchers created a 3D model to study how multiple cancer cells invade the BM collectively, finding that they use a combination of proteases and mechanical forces without relying on invadopodia.
- The study reveals that the invasion process involves both the expansion of cell volume, which stretches the BM, and local forces that help breach it, highlighting a key mechanism in cancer metastasis.
Anisotropic properties of articular cartilage in an accelerated in vitro wear test.
J Mech Behav Biomed Mater
September 2020
Many material properties of articular cartilage are anisotropic, particularly in the superficial zone where collagen fibers have a preferential direction. However, the anisotropy of cartilage wear had not been previously investigated. The objective of this study was to evaluate the anisotropy of cartilage material behavior in an in vitro wear test.
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