Corneal Cross-linking to Halt the Progression of Keratoconus and Corneal Ectasia: Seven-Year Follow-up.

Purpose: To determine long-term efficacy and safety of riboflavin/ultraviolet A corneal cross-linking (CXL).

Design: Prospective cohort study.

Methods: Thirty-six patients (36 eyes) who underwent epithelium-off CXL at a University Hospital (Guy's and St Thomas' National Health Service Foundation Trust) 6-8 years previously were examined.

Long-term follow-up of riboflavin/ultraviolet A (370 nm) corneal collagen cross-linking to halt the progression of keratoconus.

Aims: To determine long-term efficacy of riboflavin/ultraviolet A corneal cross-linking (CXL).

Methods: Thirty patients (30 eyes) who had undergone CXL following epithelial removal 4-6 years previously were examined.

Results: At 1-year mean, spherical equivalent error (SEQ) increased by +0.

Evaluation of transepithelial stromal riboflavin absorption with enhanced riboflavin solution using spectrophotometry.

Purpose: To assess transepithelial stromal riboflavin absorption with an enhanced riboflavin solution (riboflavin 0.1%, 15% dextran T500 with trometamol (Tris-[hydroxymethyl]aminomethane) and sodium ethylenediaminetetraacetic acid by analyzing light-transmission properties of ex vivo rabbit corneas.

Setting: School of Optometry and Vision Sciences, Cardiff, Wales.