Publications by authors named "Naohiko Matsushita"

Article Synopsis
  • Four years later, a CT scan showed a suspicious enlarged lymph node, leading to a diagnosis of recurrent cancer and subsequent laparoscopic surgery.
  • After surgery, the patient received adjuvant chemotherapy (CAPOX) and has remained cancer-free for over 2.5 years, highlighting the importance of close follow-up due to a 6.3% recurrence rate in similar cases.
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Purpose: The C-reactive protein-albumin-lymphocyte (CALLY) index, which simultaneously evaluates the nutritional, immunological, and inflammatory statuses, is a new prognostic biomarker in patients with various cancers; however, no study has reported the clinical significance of the CALLY index in patients with pancreatic cancer. This study aimed to investigate whether the preoperative CALLY index is a prognostic biomarker in patients undergoing surgical resection of pancreatic cancer.

Methods: We retrospectively enrolled 461 patients with pancreatic cancer who underwent surgical resection between January 2013 and December 2022.

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Article Synopsis
  • * Out of 159 patients evaluated, over half experienced loss of skeletal muscle mass during neoadjuvant chemotherapy, which correlated with a significantly lower completion rate of S-1 adjuvant chemotherapy.
  • * The findings suggest that addressing skeletal muscle loss during neoadjuvant chemotherapy could enhance the continuation of adjuvant treatment and potentially improve survival rates in these patients.
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Many studies have reported a relationship between climate factors and malaria. However, results were inconsistent across the areas. We examined associations between climate factors and malaria in two geographically different areas: lowland (lakeside area) and highland in Western Kenya.

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Background: Leptospirosis is a worldwide bacterial zoonosis. Outbreaks of leptospirosis after heavy rainfall and flooding have been reported. However, few studies have formally quantified the effect of weather factors on leptospirosis incidence.

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