Publications by authors named "Nao Takizawa"
Article Synopsis
- Brain-targeted drug and gene delivery is hindered by the blood-brain barrier (BBB), but focused ultrasound (FUS) with microbubbles can temporarily open it for better transport.
- The study developed nano-sized bubbles (NBs) using PEG-modified liposomes and combined them with the RVG-R9 peptide, which targets neuronal cells, to improve pDNA delivery across the BBB.
- In vivo tests showed successful gene delivery and expression in the brain, indicating that this new system could effectively transport genetic material for potential treatments.
