Publications by authors named "Nanyan Xiang"

Background: Recently, some observational studies have suggested potential associations between erectile dysfunction (ED) and respiratory function. However, the underlying biological mechanisms and causal relationships between ED and lung function require further investigation. This study aimed to explore the causalities between ED and lung function traits.

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  • Stress urinary incontinence (SUI) is a common issue in women caused by urethral sphincter failure, with varied prevalence rates impacted by research methods and underreporting.
  • This study uses Mendelian randomization to investigate how SUI correlates with lipid and glucose metabolism, analyzing data from large populations in the UK Biobank and ENGAGE consortium.
  • Results indicate that higher levels of total cholesterol, LDL, and HDL are linked to an increased risk of SUI, while higher fasting glucose and insulin are associated with a reduced risk, suggesting a complex relationship between metabolic factors and SUI in women.
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  • - This study investigates the causal relationship between benign prostatic hyperplasia (BPH) and cardiovascular diseases (CVDs), focusing on five specific conditions: stroke, coronary heart disease (CHD), heart failure, myocardial infarction (MI), and atrial fibrillation (AF).
  • - Using genetic data from several databases, the analysis found that BPH increases the risk for CHD and MI, but decreases the risk for stroke, suggesting a complex relationship between these conditions.
  • - The results indicate BPH might serve as a risk factor for some CVDs while offering some protection against stroke, and further research with larger sample sizes is recommended to clarify these associations.
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Background: The relaxation of the "zero-COVID" policy on Dec. 7, 2022, in China posed a major public health threat recently. Complete blood count test was discovered to have complicated relationships with COVID-19 after the infection, while very few studies could track long-term monitoring of the health status and identify the characterization of hematological parameters prior to COVID-19.

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Background: Following an initiative published by Lancet in 2002 and an IDEAL-D framework, the value of preclinical animal studies has garnered increasing attention in recent research. Numerous preclinical animal experiments tried to generate evidence to guide the development of barbed sutures. However, discernible drawbacks and incongruities in outcomes have emerged between clinical and preclinical animal studies.

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Background: The barbed suture, which can eliminate knot tying and accelerate the placement of sutures, is an innovative type of suture, whereas the benefits of cosmetic surgeries (CS) are controversial. This study aimed to comprehensively evaluate the effectiveness and safety of barbed sutures in CS.

Method: PubMed, EMBASE, Cochrane Library, and ClinicalTrials.

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