Publications by authors named "Nanwei Ye"
Article Synopsis
- Cancer is a major cause of death around the world and researchers are learning that tiny living things (like bacteria and viruses) in tumors can influence how cancer starts and how doctors can treat it.
- Recent studies show that the germs in our gut and inside tumors are important for understanding cancer better, but we still don’t know a lot about how many of these microbes are there and what they do.
- Scientists are also exploring how tiny artificial particles called exosomes can carry medicine directly to tumors, and they hope to use the variety of germs found in tumors to make cancer treatments even more effective.
The myokine CCL5 recruits subcutaneous preadipocytes and promotes intramuscular fat deposition in obese mice.
Am J Physiol Cell Physiol
May 2024
Intramuscular fat (IMF) refers to the lipid stored in skeletal muscle tissue. The number and size of intramuscular adipocytes are the primary factors that regulate IMF content. Intramuscular adipocytes can be derived from either in situ or ectopic migration.
View Article and Find Full Text PDFThe objective of this study was to investigate the impact of Lycopene and L-Carnitine, individually or in combination, on various physiological and molecular factors related to intestinal health and absorption ability in Roosters, such as intestinal morphology, serum biochemical parameters, genes involved in Lycopene uptake, nutritional transport genes, and tight junction genes. The findings of the study revealed that the combination of L-Carnitine and Lycopene supplementation had been found to increase the serum concentration levels of TP and ALB. Interestingly, the relative mRNA expression of genes responsible for Lycopene uptakes, such as and , was higher in the LC group compared to other groups.
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- The study examined how dietary curcumin affects testicular oxidative damage in breeder roosters caused by hydrogen peroxide (HO).
- Thirty-two roosters were split into four groups, with some receiving curcumin and others facing HO challenges.
- Results revealed that curcumin reduced abnormal sperm rates, improved testis health, boosted testosterone levels, and countered oxidative stress by enhancing antioxidant enzyme activity and reversing negative changes in gene expression related to reproduction and stress response.
Article Synopsis
- A study was conducted to assess how dietary Folic acid (FA) affects the reproductive performance of aged broiler breeder roosters, specifically looking at semen quality and testicular health.
- Results showed that FA supplementation significantly improved semen quality metrics such as volume, concentration, motility, and integrity in aged roosters, along with positive changes in testicular structure and function.
- The research also indicated that FA enhanced spermatogenesis-related gene expression and influenced testicular autophagy through the mTOR-signaling pathway, demonstrating its potential benefits for aging roosters' reproductive health.
Eggshell quality is subject to a significant decline in the late laying period, which results in huge economic losses. The purpose of this study was to investigate the effects of dietary mulberry-leaf flavonoids (MF) on the eggshell quality of aged breeder hens. A total of 270 (60-week-old) Qiling breeder hens were randomly assigned to 3 treatments with supplemental dietary MF doses (0, 30, and 60 mg/kg).
View Article and Find Full Text PDFDietary mulberry-leaf flavonoids supplementation improves liver lipid metabolism and ovarian function of aged breeder hens.
J Anim Physiol Anim Nutr (Berl)
November 2022
Mulberry-leaf flavonoids (MF), extracted from mulberry leaves, exert antioxidant and hypolipidemic effects. The purpose of this experimental study was to investigate the effects of dietary MF on the ovarian function and liver lipid metabolism of aged breeder hens. We used 270 (60-weeks-old) Qiling breeder hens randomly assigned in 3 treatments with supplemental dietary MF doses (0, 30, 60 mg/kg).
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- Hawthorn-leaves flavonoids (HF) show antioxidant, anti-inflammatory, and cholesterol-lowering effects and were studied for their impact on aged breeder hens' reproductive performance and liver metabolism.
- A study with 270 hens divided into three dietary groups revealed that HF significantly enhanced egg-laying and hatching rates, reduced harmful lipid levels, and increased estrogen levels in the serum.
- Additionally, a higher dose of HF improved ovarian health by increasing primordial follicles and promoting antioxidant enzyme activity, ultimately suggesting that HF supports reproductive function in older hens.
The purpose of the present study was to investigate the effects of dietary alpha-lipoic acid (ALA) supplementation on the reproductive performance of aged breeder roosters. Sixteen 50-wk-old ROSS 308 breeder roosters were randomly allocated to two groups: roosters received a basal diet (CON), or a basal diet supplemented with 300 mg/kg of ALA (ALA). The results indicated that dietary ALA supplementation significantly increased sperm concentration, motility, viability, and membrane functional integrity.
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