Publications by authors named "Nanton V"

Purpose: Transurethral resection of bladder tumor (TURBT) is the initial staging procedure for new bladder cancers (BCs). For muscle-invasive bladder cancers (MIBCs), TURBT may delay definitive treatment. We investigated whether definitive treatment can be expedited for MIBC using flexible cystoscopic biopsy and multiparametric magnetic resonance imaging (mpMRI) for initial staging.

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Background: Transurethral resection of bladder tumour has been the mainstay of bladder cancer staging for > 60 years. Staging inaccuracies are commonplace, leading to delayed treatment of muscle-invasive bladder cancer. Multiparametric magnetic resonance imaging offers rapid, accurate and non-invasive staging of muscle-invasive bladder cancer, potentially reducing delays to radical treatment.

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  • * Inpatient biopsies had significantly higher mortality rates (8% at 14 days, 26% at 30 days) compared to outpatient ones (2.2% at 14 days, 8.6% at 30 days), with older and more comorbid patients facing greater risks.
  • * Approximately 46% of patients received chemotherapy within six months, influenced by factors like age, sex, and the type of biopsy, highlighting the need for careful risk assessment and potential palliative care involvement in treatment decisions.
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  • - The study aimed to evaluate the effects of percutaneous nephrostomy for renal decompression in patients with metastatic cancer in England between 2010 and 2019, focusing on mortality and treatment outcomes post-procedure.
  • - Out of 10,932 patients analyzed, about 6.7% died within 14 days and 16.7% within 30 days post-nephrostomy, with higher mortality linked to existing comorbidities and the specialty under which the patient was treated.
  • - A quarter of the patients went on to receive chemotherapy, and nearly 44% had subsequent surgery, with younger patients more likely to receive chemotherapy and inpatient nephrostomy affecting the likelihood of undergoing further surgery.
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  • Prostate cancer (CaP) significantly impacts Black men, with 1-in-4 affected, and there is a lack of research addressing the stigma surrounding the disease in their communities.
  • The study conducted a scoping review to analyze existing literature on the stigma of CaP experienced by Black men and their families, utilizing a comprehensive search strategy across multiple databases.
  • Findings revealed that Black men's perceptions of masculinity are complexly intertwined with stigma, affecting their attitudes toward CaP screening and treatment, highlighting the importance of tailored public health initiatives and improved patient-provider communication.
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Background: Informal carers play a major role in supporting relatives and friends who are sick, disabled, or frail. Access to information, guidance, and support that are relevant to the lives and circumstances of carers is critical to carers feeling supported in their role. When unmet, this need is known to adversely affect carer resilience and well-being.

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Background: Men with prostate cancer experience immediate and long-term consequences of the disease and its treatment. They require both long-term monitoring for recurrence or progression and follow-up to identify and help manage psychosocial and physical impacts. Holistic Needs Assessment aims to ensure patient-centered continuing cancer care.

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Transurethral resection of bladder tumour (TURBT) is central to the diagnosis of muscle-invasive bladder cancer (MIBC). With the oncological safety of TURBT unknown, staging inaccuracies commonplace, and correct treatment of MIBC potentially delayed, multiparametric magnetic resonance imaging (mpMRI) may offer rapid, accurate, and noninvasive diagnosis of MIBC. BladderPath is a randomised trial comparing risk-stratified (5-point Likert scale) image-directed care with TURBT for patients with newly diagnosed BC.

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Background: Informal carers play an increasingly vital role in supporting the older population and the sustainability of health care systems. Care Companion is a theory-based and coproduced Web-based intervention to help support informal carers' resilience. It aims to provide personalized access to information and resources that are responsive to individuals' caring needs and responsibilities and thereby reduce the burdens associated with caregiving roles.

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  • This study investigates what "good care" means for men with prostate cancer from both patient and healthcare professional perspectives in the UK, highlighting the importance of effective communication and local services.
  • Semi-structured interviews were conducted with ten patients and eight healthcare professionals, analyzed with patient input to identify key themes about care quality.
  • Recommendations for improving care include enhancing resources, training, and innovative communication systems to better support patients throughout their treatment and adjustment process.
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  • This study explored a new way to provide prostate cancer care by using an online holistic needs assessment (sHNA) for patients and facilitating digital communication with healthcare professionals (HCPs).
  • Men with prostate cancer participated in a 9-month study where they completed the sHNA multiple times, and their feedback was measured using Patient Reported Outcome Measures (PROMs), focusing on their engagement and experience.
  • Results showed high initial patient engagement and satisfaction with the sHNA, but challenges with integrating hospital and general practice IT systems prevented the care model from functioning as intended, indicating the need for further improvements before larger trials.
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  • Men prostate cancer survivors experience a range of unmet needs, prompting the development of an online and cancer-specific Holistic Needs Assessment (sHNA) designed to improve service integration within healthcare.
  • A qualitative study was conducted in two phases: the first phase involved interviews with healthcare professionals and patients to gauge perceptions of the sHNA before its implementation, while the second phase assessed barriers and motivators to its use 9 to 12 months post-implementation.
  • Results showed that while both patients and healthcare professionals found the sHNA beneficial, barriers such as confidence levels, organizational changes, and patient-specific factors impacted its use, leading to a focused implementation strategy that included specialized training and peer support.
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Background: Family and other unpaid carers are crucial to supporting the growing population of older people that are living outside residential care with frailty and comorbidities. The burden associated with caring affects carers' well-being, thus limiting the sustainability of such care. There is a need for accessible, flexible, and responsive interventions that promote carers' coping and resilience, and hence support maintenance of the health, well-being, and independence of the cared-for person.

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Background: The potential of technology to aid integration of care delivery systems is being explored in a range of contexts across a variety of conditions in the United Kingdom. Prostate cancer is the most common cancer in UK men. With a 10-year survival rate of 84%, there is a need to explore innovative methods of care that are integrated between primary health care providers and specialist teams in order to address long-term consequences of the disease and its treatment as well as to provide continued monitoring for recurrence.

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  • The study examines how patients with advanced illnesses maintain their personal identities amidst the challenges of their condition, highlighting the balance between their intrinsic sense of self and extrinsic influences from their healthcare environment.
  • Through ethnographic observation and narrative interviews with 16 patients, the research identifies key factors, such as effective pain management, knowledge of resources, and collaborative care with professionals, that support identity maintenance.
  • The findings suggest that healthcare providers should engage with patients as whole individuals rather than just focusing on their medical conditions, recognizing the importance of personal identity in their overall care experience.
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  • - The study investigates the emotional labor of health care assistants in community palliative care, focusing on the experiences of both the assistants and bereaved family carers.
  • - Findings reveal that health care assistants perceive providing emotional support as a key part of their role, which family carers appreciate and recognize, demonstrating the importance of this aspect in care settings.
  • - Emotional support is expressed through relationship building, navigating boundaries in patient care, and collaborative efforts between assistants and family carers to facilitate home deaths.
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  • The study focuses on understanding the experiences of patients with advanced multimorbidity and their family carers in the context of palliative and end-of-life care, highlighting a prevalent issue in healthcare.
  • It involved detailed interviews with 37 patients and 17 carers, revealing challenges like managing numerous medications, a lack of coordinated care, and feelings of exhaustion among carers.
  • Important findings indicate that many patients and carers see deteriorating health as a natural part of aging, leading to limited engagement in advance care planning and discussions about palliative care, which are often seen as synonymous with impending death.
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  • The study aims to create a care coordination model for patients with advanced illnesses and their unpaid caregivers, focusing on their perspectives on how care should be coordinated.* -
  • Using qualitative research methods, including in-depth interviews with 56 patients and 27 caregivers across various healthcare settings in Britain, researchers analyzed the data to identify key themes and develop a cohesive model.* -
  • Findings highlight that effective care coordination is a collaborative effort involving well-informed staff and active participation from patients and caregivers, requiring adequate resources and communication tailored to their needs.*
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