[The impact of malleus processing in ossicular chain reconstruction on the therapeutic effect in patients with tympanosclerosis].

Objective: To investigate the effect of different malleus treatments on the postoperative efficacy in the tympanosclerosis patients receiving ossicular chain reconstruction.

Method: Fifty-nine patients (62 ears) with tympanosclerosis were treated by ossicular chain reconstruction. All the patients were divided into three groups, including malleus removal group (A, 24 ears), retaining only the malleus handle group (B, 18 ears) and the intact malleus group (C, 20 ears).

[Applied anatomy of facial recess and posterior tympanum related to cochlear implantation].

Objective: To investigate the related parameters of temporal bone structure in the surgery of cochlear implantation through facial recess approach so as to offer a theoretical reference for the avoidance of facial nerve injury and the accurate localization.

Method: In a surgical simulation experiment, twenty human temporal bones were studied. The correlation parameters were measured under surgical microscope.

[Applied anatomy of scala tympani inlet related to cochlear implantation].

Objective: To investigate the related parameters of the temporal bone structure for determining the position of implanting electrode into the scala tympani in cochlear implantation surgery through the facial recess and epitympanum approach.

Methods: In a surgical simulation experiment, 20 human temporal bones were studied and measured to determine the related parameters of the temporal bone structure.

Results: The distance 5.

[Therapeutic effect of ossicular reconstruction with bioceramic or porous macromolecular polyethylene partial ossicular replacement prosthesis in patients with tympanosclerosis].

Objective: To evaluate the effect of ossicular reconstruction with partial ossicular replacement prosthesis (PORP) in patients with tympanosclerosis.

Methods: The data of 31 cases of tympanosclerosis treated between 1992 and 2009 were reviewed. Of the 31 patients, 17 (17 ears) underwent ossicular reconstruction with porous macromolecular polyethylene PORP, and 14 (14 ears) with bioceramic PORP.

[Pure tone audiology for Meniere disease: a clinical analysis of 75 cases].

Objective: To analyze clinical pure tone test data in patients with Meniere disease and study the changes in the audiometic curve configuration.

Methods: A retrospective analysis was conducted of the pure tone test data in 75 cases (82 ears) from 1984 to 2008. The audiometic curve configuration was divided into 6 categories to analyze the relationship between the main curve types and the clinical stages.

[Long-term results of endolymphatic sac decompression and endolymphatic-mastoid shunting for Meniere's disease].

Objective: To investigate the efficacy of endolymphatic sac surgery for Meniere's disease, and compare the effects of endolymphatic sac decompression with endolymphatic-mastoid shunting.

Method: Twelve patients(13 ears) undergoing endolymphatic-mastoid shunting and eleven patients (11 ears) undergoing endolymphatic sac decompression were retrospectively compared for hearing results and vertigo controlled rates. All of them have been followed up for more than two years after surgery.

[Clinical analysis of 118 patients with tympanosclerosis].

Objective: To study the incidence of tympanosclerosis (TS) and the major risk factors of hearing loss.

Methods: A total of 118 TS patients (137 ears) were compared with 265 patients with chronic otitis media (COM) (311 ears) for gender, age and course of disease. The disease regions and hearing loss of the TS patients were analyzed.

[Experience of 76 cases of large vestibular aqueduct syndrome, clinical diagnosis and treatment].

Objective: To explore the disease incidence, clinical symptoms, prevention and treatment measures of the large vestibular aqueduct syndrome (LVAS).

Method: Retrospective analyse the medical history, hearing, vestibular function examination and treatment of 76 LVAS patients who were diagnosed in our department of Otolaryngology from 2002 to 2008.

Result: Most patients (93.

[Effect of surgical reconstruction of congenital aural atresia via the mastoid antrum approach: analysis of 48 cases].

Objective: To assess the effect of surgical reconstruction of congenital aural atresia via the mastoid antrum approach and investigate method for preventing postoperative atresia of the reconstructed aural canal.

Methods: From 2000 to 2008, aural canal reconstruction and tympanoplasty was performed via the mastoid antrum approach. In 48 patients with congenital aural atresia (54 ears, including 45 ears of type II, 9 ears of type III).

[Audiological assessment in 88 patients with otosclerosis].

Objective: To analyze the clinical data of the hearing in otosclerosis patients and explore their association with the clinical manifestations.

Method: A retrospective analysis of 88 otosclerosis cases (162 ears) was performed. Pure tone audiometry was performed in all the cases 1 to 3 days before the operation for speech analysis at the frequencies of 500, 1 k, 2 kHz and to determined the average pure-tone hearing threshold (PTA) and gas Bone gap (ABG).

[Therapeutic effects of small fenestra stapedotomy with semiconductor diode laser: a comparison with microdrill].

Objective: To compare the effects of small fenestra stapedotomy with semiconductor diode laser and microdrill in patients with otosclerosis.

Methods: Twenty-six patients (29 ears) undergoing stapedotomy with semiconductor diode laser and 19 patients (21 ears) with microdrill were compared for the hearing results and complication rates.

Results: No statistically significant differences were found in postoperative speech frequency and high frequency pure tone average in closing the air-bone gap between the two groups.

[Establishment of tympanosclerosis by intratympanic injection of Staphylococcus aureus in guinea pigs].

Objective: To establish a guinea pig model of tympanosclerosis and investigate the development and progression of tympanosclerosis in the tympanic membranes and middle ear mucosa.

Methods: Twenty-one healthy guinea pigs were subjected inoculation of 1x10(8)/L Staphylococcus aureus into the left middle ear cavities under general anaesthesia, with the right ears as the control, to establish models of chronic purulent otitis media. The animals were sacrificed by decapitation after 1, 3 and 6 months after model establishment for histological examination of the middle ear mucosa.

[Influence of stapedectomy on the hearing of guinea pigs].

Objective: To compare the influences of stapedectomy and small fenestra stapedotomy on the hearing of guinea pigs.

Methods: Twenty-four (48 ears) guinea pigs were randomized equally into two groups, and the left ears were subjected to stapedectomy and total stapes replacement with a prosthesis, or sham operation (12 ears) to expose the footplate of the stapes and the round window. Each guinea pig was tested by ABR perioperatively.

[Audiological assessment in 79 patients with tympanosclerosis].

Objective: To conduct audiological assessment in patients with tympanosclerosis.

Methods: A retrospective review was conducted in 79 patients with tympanosclerosis (involving 79 ears) with complete records, including 30 patients (30 ears) with fixed Malleus-incus complex, 29 (29 ears) with fixed stapes, and 20 (20 ears) with fixations of both the stapes footplate and the Malleus-incus complex. Audiometry was performed for all the patients one or two days before operation, and the audiological features of the patients were compared between the 3 groups.

[Effects of different surgical techniques for otosclerosis].

Objective: To compare the effectiveness of three surgical techniques for otosclerosis.

Method: Retrospective analysis was made of patients with otosclerosis who had received surgical treatment during 1993-2005. There were totally 70 patients (76 ears) in which 30 patients (33 ears) underwent total stapedectomy with original stapes, 24 patients (27 ears) underwent small fenestra stapedotomy with Teflon piston artificial stapes and 16 patients (16 ears) underwent stapes mobilization or elevation.

[Effects of ossicular reconstruction with partial ossicular replacement prosthesis in patients with tympanosclerosis].

Objective: To evaluate the effect of ossicular reconstruction with partial ossicular replacement prosthesis (PORP) in patients with tympanosclerosis.

Methods: The data of 28 cases of tympanosclerosis treated between 1992 and 2006 were reviewed. Of the 28 patients, 14 (14 ears) underwent ossicular reconstruction with PORP and 14 (14 ears) had ossicular mobilization, and all the patients were followed-up for 3-24 months.

[Effects of small fenestra stapedotomy in comparison with total stapedectomy].

Objective: To compare the effect of small fenestra stapedotomy and total stapedectomy in patients with otosclerosis.

Methods: Twenty-seven patients (30 ears) undergoing small fenestra stapedotomy and 36 patients (43 ears) receiving total stapedectomy were compared for hearing results and complication rates.

Results: No statistically significant differences were seen in postoperative speech pure tone average in closing air-bone gap between the two groups.

[Analysis of auditory steady-state response to multiple simultaneous stimuli and cochlea morphology in guinea pigs with posterior semicircular canal fistula].

Objective: To observe the changes of auditory steady-state response (ASSR) threshold in guinea pigs with posterior semicircular canal fistula.

Methods: In 10 guinea pigs, a window was opened in the posterior semicircular canal of the left ear with the right ear serving as the control for testing the ASSR under anesthesia with pentobarbital sodium.

Results: The mean and standard deviation of ASSR threshold (dB SPL) at 0.

[Treatment of operation of carotid body tumor and glomus jugular tumor].

Objective: To study the clinical characteristics and outline of surgery for carotid body tumor and glomus jugular tumor.

Method: Incisions of anterior border of sterno-mastoid muscle was made for simple carotid body tumor. A big S shape incisions and infratemporal fossa approach were employed which exposure the jugular foramen and apex of petrous for glomus jugular tumor or suffered carotid body tumor and glomus jugular tumor simultaneously in same side.

[Intranasal endoscopic surgery on the anterior cranial fossa via the anterior skull base].

Objective: To explore the possibility of performing anterior cranial fossa surgery by an intranasal endoscope via the anterior skull base.

Method And Results: A rare case of accidental insertion of chopstick into the anterior cranial fossa as deep as 6.5 cm was reviewed and analyzed.

[Preparation and clinical application of Teflon-wire piston and stapes height measurer].

With Teflon, and a tiny stainless steel needle of a number 7 injector and an acupuncture needle,Teflon-piston and a measurer of the stapes height were prepared respectively of stapedectomy for treatment of otosclerosis. Good clinical results were achieved with these simple and useful devices.