Publications by authors named "Nanny Natalia Mulyani Soetedjo"
The thyroid gland is responsible for metabolism, as well as cardiac function and the peripheral vascular system. Thyroid dysfunctions are associated with an increase in the risk of cardiovascular diseases, including heart failure and coronary heart disease atrial fibrillation, by impairing heart contractility, stroke volume, heart rate, peripheral vascular resistance, and electrical activity. Thyroid dysfunctions also alter several cardiovascular risk factors, such as atherosclerosis, hypertension, and dyslipidemia, as well as causing stroke, which is associated with atrial fibrillation.
View Article and Find Full Text PDFAims: The primary objective of this investigation is to examine the efficacy and safety of insulin icodec when compared to regular basal insulin for the management of type 2 diabetes mellitus (T2DM).
Methods: A comprehensive search was conducted on the Cochrane Library, Scopus, ClinicalTrials.gov, and Medline databases up until August 19th, 2023.
Different doses of imeglimin for management of type 2 diabetes mellitus: a systematic review, meta-analysis, and meta-regression of randomized clinical trials.
Expert Rev Endocrinol Metab
January 2024
Background: A new medication for type 2 diabetes mellitus (T2DM) called imeglimin can target all three organs involved in the pathogenesis of DM, namely the liver, skeletal muscles, and pancreas. This research seeks to examine the most efficacious and safe dose of imeglimin for the management of T2DM.
Research Design And Methods: Using particular keywords, we searched the CENTRAL, Medline, Scopus, and ClinicalTrials.
Immune system dysregulation in people with diabetes mellitus (DM) increases the risk of acquiring severe infection. We compared the clinical characteristics and laboratory parameters of coronavirus disease 2019 (COVID-19) patients with and without DM and estimated the effect of DM on mortality among COVID-19 patients. A retrospective cohort study collecting patients' demographic, clinical characteristics, laboratory parameters and treatment outcomes from medical records was conducted in a hospital in Bandung City from March to December 2020.
View Article and Find Full Text PDFBackground And Aims: The term metabolic dysfunction-associated fatty liver disease (MAFLD) has been established to better define patients with fatty liver disease who also present with metabolic dysfunction. However, the association between MAFLD and chronic-kidney disease (CKD) remains elusive.
Methods: .
Purpose: The relationship between thyroid metabolism and coronavirus disease 2019 (COVID-19) inflammation has been extensively investigated. This meta-analysis aimed to evaluate the prognostic properties of unspecified thyroid disorders, hypothyroidism and hyperthyroidism for predicting poor COVID-19 outcomes.
Methods: We conducted systematic literature searching through multiple databases-PubMed, EBSCO and CENTRAL up until 27 September 2021.
Article Synopsis
- The study aimed to analyze how thyroid disorders during hospital admission affect the prognosis of COVID-19 patients, focusing on outcomes like severity and mortality.
- It involved a review of 20 studies with 24,734 patients, finding that thyroid disorders significantly increased the risk of severe COVID-19 and negative outcomes.
- Key factors such as age and hypertension influenced this relationship, while thyroid disorders were associated with a 38% chance of poor outcomes compared to 15% in patients without them.
Background: Coronavirus disease 2019 (COVID-19) elicits robust inflammatory reaction that may result in a declining albumin serum level. This meta-analysis aimed to evaluate the prognostic properties of hypoalbuminemia for poor prognosis and factors that may influence the relationship.
Method: A systematic literature search of PubMed was conducted from inception to April 22, 2021.