Side-Opened Hollow Fiber-Based SPR Sensor for High Refractive Index Detection.

To facilitate the sensor fabrication and sensing operation in microstructured optical fiber-based surface plasmon resonance (SPR) sensors for high refractive index (RI) detection, we propose a special hollow fiber-based SPR sensor that comprises an opening on its body side and a thin gold layer coated on its outer surface. The analyte is able to flow into the hollow core through the side-opening to form new fiber core, with the Gaussian-like mode propagating in it. We investigate the sensing performance of the proposed sensor in a higher RI range of 1.

Cross-sensitivity immune SPR sensor based on fan-shaped microstructured optical fiber for temperature and refractive index sensing.

To avoid coating and filling into the fiber holes, facilitate the phase-matching and eliminate cross-sensitivity problems, we propose a surface plasmon resonance sensor based on a fan-shaped microstructured optical fiber (MOF) for the simultaneous sensing of temperature and refractive index (RI). The fan-shaped structure is fabricated by polishing two sides of MOF with an angle of 120°. One side is coated with the gold film and polydimethylsiloxane layer for temperature sensing, and the other side is only coated with the gold film for RI sensing.

Efficient and Stable Blue Perovskite Light-Emitting Devices Based on Inorganic CsPbBr Spaced Low-Dimensional CsPbBr through Synergistic Control of Amino Alcohols and Polymer Additives.

Perovskite light-emitting devices (PeLEDs) have drawn a great deal of attention because of their exceptional optical and electrical properties. However, as for the blue PeLEDs based on low-dimensional (LD) CsPbBr, the low conductivity of the widely used organic spacers as well as the difficulty of forming pure and uniform LD CsPbBr phase have severely inhibited the device performance such as stability and efficiency. In this work, we report an effective strategy to obtain high-quality LD CsPbBr by using a novel spacer of inorganic CsPbBr instead of the common long-chain ammonium halides.

Efficient Thermally Evaporated Perovskite Light-Emitting Devices via a Bilateral Interface Engineering Strategy.

Physical vapor deposition has emerged as a promising strategy for efficient and stable all-inorganic perovskite light-emitting devices (PeLEDs). However, the thermally evaporated PeLEDs still suffer from unsatisfactory optoelectrical performance because of the massive nonradiative defects. Herein, we demonstrate an efficient bilateral interfacial defect-passivation strategy toward high-performance PeLEDs with a thermally deposited CsPbBr emissive layer (EML).

Design and analysis of trench-assisted dual-mode multi-core fiber with large-mode-field-area.

A novel trench-assisted dual-mode multi-core fiber with large-mode-field-area is proposed. The structure consists of 17 conventional cores and two air holes according to a regular hexagon, which can realize strict dual-mode transmission. The structural parameters' effect on mode transmission characteristics, mode-field-area, and bending loss are analyzed systematically.

LINC00997/MicroRNA 574-3p/CUL2 Promotes Cervical Cancer Development via Mitogen-Activated Protein Kinase Signaling.

Cervical cancer (CC) is a common gynecological malignancy with high morbidity and mortality. Mounting evidence has highlighted that long noncoding RNAs are essential regulators in cancer development. Long intergenic non-protein-coding RNA 997 (LINC00997) was identified for study due to its high expression in CC tissues.

MRPL15 is a novel prognostic biomarker and therapeutic target for epithelial ovarian cancer.

Purpose: To analyze the role of six human epididymis protein 4 (HE4)-related mitochondrial ribosomal proteins (MRPs) in ovarian cancer and selected MRPL15, which is most closely related to the tumorigenesis and prognosis of ovarian cancer, for further analyses.

Methods: Using STRING database and MCODE plugin in Cytoscape, six MRPs were identified among genes that are upregulated in response to HE4 overexpression in epithelial ovarian cancer cells. The Cancer Genome Atlas (TCGA) ovarian cancer, GTEX, Oncomine, and TISIDB were used to analyze the expression of the six MRPs.

Numerical Analysis and Recursive Compensation of Position Deviation for a Sub-Millimeter Resolution OFDR.

We analyze the source of the position deviation and propose a demodulation recursive compensation algorithm to ensure a sub-millimeter resolution in improved optical frequency domain reflectometry. The position deviation between the geometric path and optical path changes with the temperature or strain, due to the elastic-optic and thermal-optic effects. It accumulates along the fiber and becomes large enough to affect the spectral correlation between the measured and reference spectra at the fiber end.

Fluorinated Polyimide-Film Based Temperature and Humidity Sensor Utilizing Fiber Bragg Grating.

We propose and demonstrate a temperature and humidity sensor based on a fluorinated polyimide film and fiber Bragg grating. Moisture-induced film expansion or contraction causes an extra strain, which is transferred to the fiber Bragg grating and leads to a humidity-dependent wavelength shift. The hydrophobic fluoride doping in the polyimide film helps to restrain its humidity hysteresis and provides a short moisture breathing time less than 2 min.

Boosting the Efficiency and Stability of Perovskite Light-Emitting Devices by a 3-Amino-1-propanol-Tailored PEDOT:PSS Hole Transport Layer.

Properties of the underlying hole transport layer (HTL) in perovskite light-emitting devices (PeLEDs) play a critical role in determining the optoelectronic performance through influencing both the charge transport and the quality of the active perovskite emission layer (EML). This work focuses on manipulating the carrier transport behavior and obtaining a high-quality EML film by tailoring the poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) HTL with previously unused amino alcohol 3-amino-1-propanol (3AP). The modified PEDOT:PSS rendered a deeper work function that is more suitable for the hole injection from the HTL to EML.

Surface Plasmon Resonance Sensor Based on Dual-Side Polished Microstructured Optical Fiber with Dual-Core.

A surface plasmon resonance (SPR) sensor based on a dual-side polished microstructured optical fiber (MOF) with a dual core is proposed for a large analyte refractive index (RI; ) detection range. Gold is used as a plasmonic material coated on the polished surface, and analytes can be directly contacted with the gold film. The special structure not only facilitates the fabrication of the sensor, but also can work in the range of 1.

Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation.

Purpose: To identify key pathogenic genes and reveal the potential molecular mechanisms of endometrial cancer (EC) using bioinformatics analysis and immunohistochemistry validation.

Materials And Methods: Through weighted gene co-expression network analysis (WGCNA), a co-expression network was constructed based on the top 25% variant genes in the GSE50830 dataset downloaded from gene expression omnibus (GEO). GO and KEGG pathway enrichment analyses were performed using the DAVID online tool.

Improved Performance for Thermally Evaporated Perovskite Light-Emitting Devices via Defect Passivation and Carrier Regulation.

Efficient inorganic perovskite light-emitting devices (PeLEDs) with a vacuum-deposited CsPbBr emission layer were realized by introducing an ultrathin 2-phenylethanamine bromide interlayer. The PEA cations not only passivated the nonradiative defects by terminating on the CsPbBr surface but also regulated the charge transport to balance the hole and electron transport. Consequently, the PeLEDs exhibit significantly promoted performance with a turn-on voltage of 3 V, a maximum current efficiency of 14.

External oxidant-free alkylation of quinoline and pyridine derivatives.

A novel and efficient method for the generation of alkyl radicals and the alkylation of quinoline and pyridine derivatives under mild conditions has been developed. This strategy allows the direct alkylation of heteroaromatics in the absence of an external oxidant. A preliminary mechanistic study suggests that the present reaction probably proceeds via an intermolecular HAT process.

A Large Detection-Range Plasmonic Sensor Based on An H-Shaped Photonic Crystal Fiber.

An H-shaped photonic crystal fiber (PCF)-based surface plasmon resonance (SPR) sensor is proposed for detecting large refractive index (RI) range which can either be higher or lower than the RI of the fiber material used. The grooves of the H-shaped PCF as the sensing channels are coated with gold film and then brought into direct contact with the analyte, which not only reduces the complexity of the fabrication but also provides reusable capacity compared with other designs. The sensing performance of the proposed sensor is investigated by using the finite element method.

Transvaginal excision of rectal stromal tumors: case reports and a literature review.

Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Rectal locations are very rare, and minimally invasive surgery is a good choice for the treatment of rectal GISTs.

Case Presentation: Two women each had a mass located on the lower vaginal-rectal space as determined by transvaginal ultrasound (TV-US), pelvis MR imaging, and colonoscopy.

Palladium-Catalyzed Hiyama Cross-Couplings of Arylsilanes with 3-Iodoazetidine: Synthesis of 3-Arylazetidines.

The first palladium-catalyzed Hiyama cross-coupling reactions of arylsilanes with 3-iodoazetidine were described. The protocol provides a convenient access to a variety of useful 3-arylazetidines which are of great interest in pharmaceutical laboratories in moderate to good yields (30%-88%). In addition, this strategy has the advantage of easy operation and mild reaction conditions.

A Temperature Plasmonic Sensor Based on a Side Opening Hollow Fiber Filled with High Refractive Index Sensing Medium.

A surface plasmon resonance temperature sensor based on a side opening hollow-core microstructured optical fiber is proposed in this paper. This design employs a gold nanowire to excite the plasmon mode, and can be easily filled with the sensing medium through the side opening of the fiber, which not only simplifies the fabrication of the sensor but can also use the high refractive index sensing medium. The coupling characteristics, sensing performance and fabrication tolerance of the sensor are analyzed by using the finite element method.

Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis.

Inadequate trophoblast invasion and increased trophoblast apoptosis cause serious pregnancy complications. Pleckstrin homology-like domain, family Α, member 2 (PHLDA2) has been linked to fetal size at birth and growth restriction in a number of studies. However, the impact of PHLDA2 on trophoblast function had not been studied previously, to the best of our knowledge.

The expression of the imprinted gene pleckstrin homology-like domain family A member 2 in placental tissues of preeclampsia and its effects on the proliferation, migration and invasion of trophoblast cells JEG-3.

Preeclampsia (PE) is one of the most common hypertensive disorders and is a leading cause of morbidity and mortality for pregnant women and perinatal babies. Additionally, pleckstrin homology-like domain family A member 2 (PHLDA2) is associated with placental dysfunction. However, the effect of PHLDA2 on trophoblast cell proliferation, migration and invasion has not been investigated.

Surface plasmon resonance sensor based on D-shaped microstructured optical fiber with hollow core.

To solve the phase matching and analyte filling problems in the microstructured optical fiber (MOF)-based surface plasmon resonance (SPR) sensors, we present the D-shaped hollow core MOF-based SPR sensor. The air hole in the fiber core can lower the refractive index of a Gaussian-like core mode to match with that of a plasmon mode. The analyte is deposited directly onto the D-shaped flat surface instead of filling the fiber holes.

Nonlinear reduction in risk for colorectal cancer by oral contraceptive use: a meta-analysis of epidemiological studies.

Purpose: Although the relationship between oral contraceptive (OC) use and colorectal cancer (CRC) risk has been studied extensively, the results of epidemiological studies are controversial. Therefore, we carried out a meta-analysis of epidemiological studies to summarize the available evidence and to quantify the potential dose-response relation.

Methods: We searched PubMed database for studies of OC use and CRC risk that were published until the end of March 2014.

Surface plasmon resonance temperature sensor based on photonic crystal fibers randomly filled with silver nanowires.

We propose a temperature sensor design based on surface plasmon resonances (SPRs) supported by filling the holes of a six-hole photonic crystal fiber (PCF) with a silver nanowire. A liquid mixture (ethanol and chloroform) with a large thermo-optic coefficient is filled into the PCF holes as sensing medium. The filled silver nanowires can support resonance peaks and the peak will shift when temperature variations induce changes in the refractive indices of the mixture.

Breastfeeding and ovarian cancer risk: a meta-analysis of epidemiologic studies.

Background: Epidemiologic studies have yielded inconsistent findings between breastfeeding and epithelial ovarian cancer (EOC) risk.

Objective: We performed a meta-analysis to summarize available evidence of the association between breastfeeding and breastfeeding duration and EOC risk from published cohort and case-control studies.

Design: Relevant published studies were identified by a search of MEDLINE through December 2012.

A reflective photonic crystal fiber temperature sensor probe based on infiltration with liquid mixtures.

In this paper, a reflective photonic crystal fiber (PCF) sensor probe for temperature measurement has been demonstrated both theoretically and experimentally. The performance of the device depends on the intensity modulation of the optical signal by liquid mixtures infiltrated into the air holes of commercial LMA-8 PCFs. The effective mode field area and the confinement loss of the probe are both proved highly temperature-dependent based on the finite element method (FEM).