Catalyst-free electrochemical trifluoromethylation of coumarins using CFSONHNHBoc as the CF source.

An efficient electrochemical trifluoromethylation of coumarins using CFSONHNHBoc as the source of the trifluoromethyl group was developed. Under catalyst-free and external oxidant-free electrolysis conditions, a range of 3-trifluoromethyl coumarins were obtained in moderate to good yields. The method could be easily scaled up with moderate efficiency.

Actualizing a High-Energy Bipolar-Stacked Solid-State Battery with Low-Cost Mechanically Robust Nylon Mesh-Reinforced Composite Polymer Electrolyte Membranes.

To meet the rapidly growing and diversified demand for energy storage, advanced rechargeable batteries with high-performance materials and efficient battery configuration are widely being exploited and developed. Bipolar-stacked electrode coupling with solid-state electrolytes enables achieving batteries with high output voltage, high energy density, and simple components. Here, a polymer electrolyte membrane is designed with polyethylene oxide containing bis(trifluoromethanesulfonyl)-imide as the electrolyte, succinonitrile as the plasticizer, and nylon mesh as a reinforcement for the bipolar-stacked battery.

A pharmacokinetic study of diclofenac sodium in rats.

The aim of the present study was to examine the pharmacokinetics of a single intravenous injection (i.v.) and oral administration (p.