Publications by authors named "Nanlan Yang"
Article Synopsis
- Researchers are tackling the challenges of using MEK inhibitors in cancer treatment due to off-target toxicity and the need for better predictive markers; they suggest that E-cadherin levels could help predict MEK inhibitor effectiveness.
- Instead of using traditional methods that require frequent high-dose injections, the study introduces a new approach with a thermosensitive and biodegradable hydrogel that can release MEK inhibitors and doxorubicin locally and sustainably.
- This innovative hydrogel-liposome system shows promise in reducing tumor growth and improving survival rates in E-cadherin-positive triple-negative breast cancer models, while minimizing toxicity.
Aim: To investigate the feasibility of assessing the ecacy of non-surgical treatment for gastric lymphoma using oral contrast-enhanced ultrasound (OCEUS) and double contrast-enhanced ultrasound (DCEUS).
Material And Methods: A total of 27 patients with gastric lymphoma treated nonoperatively were included in this retrospective study. The ecacy was evaluated using OCEUS and CT, respectively, and the results were tested for kappa concordance.
Sonodynamic therapy (SDT), a promising alternative for cancer therapy, utilizes a sonosensitizer combined with ultrasound (US) irradiation to damage tumor cells/tissues for therapeutic purposes. The ability of sonosensitizers to specifically accumulate in tumor cells/tissues could greatly influence their therapeutic efficiency. In this work, we report the use of US-activated sonosensitizer (IR780)-based nanodroplets (IR780-NDs) for SDT, which provide numerous benefits for killing cancer cells compared with traditional methods.
View Article and Find Full Text PDFWhat is the Optimal Age for Students to Receive Cardiopulmonary Resuscitation Training?
Prehosp Disaster Med
August 2018
Article Synopsis
- The study investigates whether the age recommendations for CPR training are suitable for East Asian students, similar to those for Caucasian students.
- A total of 360 students from six schools participated in a 60-minute CPR training session, and their compression skills were assessed shortly after.
- Results show that while adequate compression skills could be achieved by age 12, younger students, as young as six, were also able to demonstrate effective CPR techniques, suggesting that training can be beneficial at a younger age.