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Publications by authors named "Nanji Yang"

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Tuning Recombinant Perlecan Domain V to Regulate Angiogenic Growth Factors and Enhance Endothelialization of Electrospun Silk Vascular Grafts.
Shouyuan Jiang Nanji Yang Richard P Tan Edward S X Moh Lu Fu

Adv Healthc Mater

September 2024

Article Synopsis
  • Synthetic vascular grafts often fail due to poor blood compatibility and narrowing, presenting a significant challenge in medical procedures.
  • The engineered form of perlecan domain V (rDV) enhances blood vessel healing by supporting the signaling of growth factors and promoting endothelial cell growth.
  • Testing on electrospun silk fibroin vascular grafts shows that coating them with rDV improves graft performance and encourages the formation of blood vessel lining in animal models.
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