Publications by authors named "Nani Oliveira-Carvalho"
Phenotypic Timeline Kinetics, Integrative Networks, and Performance of T- and B-Cell Subsets Associated with Distinct Clinical Outcome of Severe COVID-19 Patients.
Microorganisms
November 2024
The present study aimed to evaluate the kinetics of the phenotypic profile and integrative networks of T/B-cells in severe COVID-19 patients, categorized according to disease outcome, during the circulation of the B.1.1.
View Article and Find Full Text PDFArticle Synopsis
- A study analyzed the immune response (specifically IgA and IgG antibodies) in COVID-19 patients, focusing on the spike and nucleocapsid proteins of the virus to relate it to disease severity.
- The research found that hospitalized patients with severe symptoms had a significantly stronger IgG response compared to those with mild symptoms, indicating a correlation between antibody levels and disease outcome.
- The findings suggest that tracking specific antibody responses could help in understanding disease progression and potentially improving patient outcomes.
Although the genus Trichoderma is widely used as a biocontrol agent in crops, little is known about its potential impact on the human immune system. In mice, our group has shown that exposition to T. asperelloides spores lead to reduced neutrophil counts in the peripheral blood and in the peritoneal cavity.
View Article and Find Full Text PDFBackground: Manaus, located in the Brazilian rainforest, has experienced two health system collapses due to the coronavirus disease 2019 (COVID-19) pandemic. However, little is known about which groups among the general population have been most affected.
Methods: A convenience sampling strategy via online advertising recruited 3046 adults between 19 August 2020 and 2 October 2020.