The ultrastructure of formed white blood elements (neutrophils) in schizophrenia.

A comparative electronmicroscopic study of neutrophils in schizophrenic patients and in healthy control subjects has revealed a certain difference in the ultrastructure of blood cell formation. This difference concerns the coarse-grained chromatin, the osmiophility of nuclear membrane, the enlargement of perinuclear halo, the enlightenment of matrix, the enlargement of glycogen granules, the swelling of mitochondria, the change in the amount of free ribosomes, an increase in the number of azurophilic granules and a decrease in the specific ones.