Publications by authors named "Nandini Randhave"
Article Synopsis
- - The study develops polyvinyl alcohol-chitosan-loaded oleanolic acid nanofibers (PVA-CS-OLA-NFs) aimed at treating bacterial infections, with detailed characterization methods including SEM and FTIR revealing their consistent structure and effective drug loading.
- - In vitro tests show that these nanofibers have a drug release rate of about 51.82% over 24 hours and are non-hemolytic, indicating they don't damage human blood cells.
- - The PVA-CS-OLA-NFs exhibit strong antibacterial activity against S. aureus, promote enhanced wound healing compared to existing treatments, and their effectiveness is monitored via advanced imaging techniques that assess blood flow and oxygen levels.
Atherosclerosis is a vascular intima condition in which any part of the circulatory system is affected, including the aorta and coronary arteries. Indocyanine green (ICG), a theranostic compound approved by the FDA, has shown promise in the treatment of coronary atherosclerosis after incorporation into nanoplatforms. By integration of ICG with targeting agents such as peptides or antibodies, it is feasible to increase its concentration in damaged arteries, hence increasing atherosclerosis detection.
View Article and Find Full Text PDFNanotheranostics is a rapidly developing field that integrates nanotechnology, diagnostics, and therapy to provide novel methods for imaging and treating wide categories of diseases. Targeted nanotheranostics offers a platform for the precise delivery of theranostic agents, and their therapeutic outcomes are monitored in real-time. Presently, in vivo magnetic resonance imaging, fluorescence imaging, ultrasound imaging, and photoacoustic imaging (PAI), etc.
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