Nitroquinolone Fused Salicyl and Naphthyl Hydrazone Fluorescent Probes for the Detection of Feand Pb Ions.

The application of quinolones stretches over a large umbrella of medicinal field as well as chemosensor due to the presence of privileged heterocyclic aromatic rig system. Salicyl and Naphthyl Hydrazide motifs are also established fluorophore groups. Therefore in this work, we have designed and synthesized Salicyl hydrazide (3a-c) and naphthyl hydrazide fused nitroquinolones (5a-c) investigated for their fluorescent behaviour.

Azine Based Oligoesteric Chemosensors for Cu Ion Detection: Synthesis, Structural Characterization, and Theoretical Investigations.

Synthesized monomer and its three oligoesters were characterized by techniques such as H, C{H}, IR, UV, GPC and applied to chemosensor applications. A series of metal ions was studied with fluorophores to evaluate the sensitivity towards Cu ion. The fluorophores results exhibit the selective and sensitive "Turn off" fluorescence response with Cu ion in DMF/HO (1:1, pH: 7.

Salicylaldehyde built fluorescent probe for dual sensing of Al, Zn ions: Applications in latent fingerprint, bio-imaging & real sample analysis.

This Schiff base chemosensor (SNN) detected dual ions, Al and Zn ions selectively. Fluorescence spectrum investigations showed that Al ions increased fluorescence intensity, notably at 493 nm. Introducing Zn ions caused a significant blue shift of roughly ∼65 nm at a wavelength of 434 nm, resulting in a notable change in fluorescence intensity.

Naphthalene derived Schiff base as a reversible fluorogenic chemosensor for aluminium ions detection.

Schiff base (HNPD) was achieved by reacting 2-hydroxy-1-naphthaldehyde with N-phenyl-o-phenylenediamine in enthanol medium. The spectroscopic analyses were done to establish the formation of Schiff base apparently. Further, synthesized Schiff base conjugate was successfully used as a fluorogenic chemosensor to detect aluminium ions (Al) with high fluorescence amplification among the other interfering various metal ions.

A coumarin hydrazone appended rotatable phenolic scaffold as fluorescent chemosensor for Ag ions and its bio imaging applications.

A coumarin hydrazone-phenol conjugate, COH4 was designed, synthesized and utilized for the cation sensing studies by fluorimetry studies. The synthesized chemosensor was completely characterized by the usual spectroscopic and analytical studies. The COH4 receptor was examined for the detection of metal ions, in which it had a noticeable blue shifted fluorescence enhancement for Ag ions.

Positional Isomeric Symmetric Dipodal Receptors Dangled with Rotatable Binding Scaffolds: Fluorescent Sensing of Silver Ions and Sequential Detection of l-Histidine and Their Multifarious Applications.

Three simple dipodal artificial acyclic symmetric receptors, , , and , driven by positional isomerism based on xylelene scaffolds were designed, synthesized, and characterized by H NMR, C NMR, and mass spectroscopy techniques. Probes , , and demonstrated selective detection of Ag metal ions and amino acid l-histidine in a DMSO-HO solution (1:1 v/v, HEPES 50 mM, pH = 7.4).

Anthracene benzene conjugate (ABC): An asymmetric Schiff base for the selective detection of Ag ion using fluorimetry and its applications.

Anthracene based chemosensor ABC has been synthesized and characterized through H, C NMR, mass spectral studies. UV absorption and emission studies performed to identify the sensing behavior of chemosensor ABC. The probe ABC, originally bright fluorescent, selectively sense Ag ion by the quenching the fluorescence intensity through a "Switch On-off" process and quench the fluorescence due to the heavy atom effect interaction with the free chemosensor.

A lead selective dimeric quinoline based fluorescent chemosensor and its applications in milk and honey samples, smartphone and bio-imaging.

Dimeric quinoline-based Schiff base was developed (DQS) for the specific detection of Pb ion via fluorimetry. DQS coordinates with Pb, a variation in fluorescence intensity with enhanced radical blue shift was observed due to the restriction of CN rotation, CN isomerization, and photoinduced electron transfer (PET) mechanisms. In addition, the intramolecular charge transfer (ICT) from electron-donating morpholine to phenylene diamine acceptor linked quinoline bridge is responsible for the blue-shifted fluorescence enhancement in the DQS-Pb complex.

COVID-19: Invasion, pathogenesis and possible cure - A review.

Today, Coronavirus disease (COVID-19) which is believed to be transmitted from bats to humans where the people of Wuhan city, China exposed to the wet animal market is an important international public health anxiety (Xiong et al., 2020). Although, several measures were undertaken to treat the diseases by various medical advancements and by a variety of treatment procedures, still the mortality is higher.

Graphene oxide-rhodamine nanocomposite for picomolar detection of chromium(III) by fluorimetry and its biofilm inhibition.

Graphene oxide-rhodamine B hydrazide (GO-RhB) nanocomposite was prepared by a simple chemical method and characterized by various spectroscopic and analytical techniques. GO-RhB nanocomposite potentially detects Cr ion (excitation/emission = 550 nm/572 nm) via fluorescence turn "on-off" approach. This composite showed high binding affinity (10 M) with Cr and a+ limit of detection (LOD) down to picomolar concentration (LOD = 85.

A photoswitchable "turn-on" fluorescent chemosensor: Quinoline-naphthalene duo for nanomolar detection of aluminum and bisulfite ions and its multifarious applications.

A quinoline-naphthalene duo-based Schiff base probe (R) was synthesized and characterized by the usual spectroscopic and single-crystal X-ray crystallographic techniques. Probe R detects Al and HSO ions via the fluorescent turn-on approach by dual pathways i.e.

Fabrication of graphene oxide-p-phenylenediamine nanocomposites as fluorescent chemosensors for detection of metal ions.

In this work, graphene oxide-p-Phenylenediamine nanocomposites of two different ratios of Graphene oxide: p-Phenylenediamine (1:1 and 1:5) were prepared and characterized by using analytical, spectroscopic and microscopic studies (GO-pPD 11 and GO-pPD 15). These nanocomposites were employed as fluorescent chemosensors for sensing potential cations. Remarkably, graphene oxide-p-Phenylenediamine nanocomposites of ratio 1:1 (GO-pPD 15) was selective and sensitive to Ag ions, whereas the graphene oxide-p-Phenylenediamine nanocomposites of ratio 1:5 (GO-pPD 15) was selective to Ceions.

Rhodanine-based fluorometric sequential monitoring of silver (I) and iodide ions: Experiment, DFT calculation and multifarious applications.

A simple rhodanine derived fluorophoric unit has been designed for selective detection of Ag and I ions in DMSO-HO medium. The sensor R1 showed an obvious "turn-on" fluorescence response toward Ag due to the inhibition of both C-N single bond free rotation, internal charge transfer (ICT) and the formation of chelation enhanced fluorescence (CHEF) effects. The fluorescence quantum yield (Φ) was increased from 0.

Synthesis, antibacterial, anti-oxidant and molecular docking studies of imidazoquinolines.

Quinoline and imidazole derivatives have been playing a significant role in functional bioactivities and were potentially used as antibacterial, antifungal, anticancer, and anti-inflammatory drugs. Owing to the limitation of drug resistance, herein we synthesized thio-, chloro-, and hydroxyl-functionalized various imidazoquinolines by molecular hybridization approach. All the imidazoquinoline derivatives were examined for their antibacterial activity against selected bacterial pathogens by the agar well diffusion method.

Adsorption of nickel ions from electroplating effluent by graphene oxide and reduced graphene oxide.

Heavy metal pollution in the water bodies causes a serious threat to all living beings. Extended exposure of heavy metals such as nickel (Ni) ions causes cancer. Henceforth, the current study investigated the removal of Ni ions from the electroplating effluent using nanocomposites namely, Graphene Oxide (GO) and Reduced Graphene Oxide (rGO) in the presence of various factors such as contact time, pH, agitation speed and sorbent dosage.

Quinoline based reversible fluorescent probe for Pb; applications in milk, bioimaging and INHIBIT molecular logic gate.

We report the modular design and synthesis of an amine dangled Schiff base quinoline-morpholine conjugate (QMC) for highly selective detection of Pb ions via fluorimetry. The sensing strategy of QMC towards Pb ion exhibits a large blue shift with fluorescent enhancement via the intramolecular charge transfer (ICT) process. At the same time, QMC coordination with Pb, the CN single bond rotation between quinoline and morpholine rings and the CN isomerization process were blocked.

Novel Quinoline-Based Thiazole Derivatives for Selective Detection of Fe, Fe, and Cu Ions.

New quinoline-based thiazole derivatives and were synthesized and characterized by various spectroscopic and single-crystal X-ray crystallographic studies. The metal-sensing properties of the probes were further examined by absorption and fluorescence spectrometry. The fluorescence intensity of and was remarkably quenched during the addition of Fe, Fe, and Cu ions in THF/HO (1:1) at pH = 7.

Triphenyl-imidazole based reversible coloro/fluorimetric sensing and electrochemical removal of Cu ions using capacitive deionization and molecular logic gates.

A simple hydroxyl-substituted triphenyl-imidazole based receptor (HTPI) which selectively detects Cu ion by colorimetric and fluorimetric methods was developed. HTPI detects the Cu ions with the absorption enhancement and fluorescence quenching by the possible ligand to metal charge transfer (LMCT) and the chelation-enhanced quenching (CHEQ) approaches, respectively. HTPI showed high selectivity and sensitivity for Cu ions detection over other interfering and competing metal ions.

Sol-Gel Synthesis of Ce Sr Fe Zn O [0 ≤ ≤ 0.45] Superparamagnetic Oxide Systems and Its Magnetic, Dielectric, and Drug Delivery Properties.

In this work, we have successfully synthesized superparamagnetic nanocomposites, Ce Sr Fe Zn O (0 ≤ ≤ 0.45) (CSFZ) (TA1-TA4: = 0, 0.15, 0.

TiO₂ Decorated Graphene as a Fluorescent Chemosensor for the Detection of Silver Ions.

In this report, a new design is proposed for the detection of silver ions using Graphene Oxide-Titanium oxide (GO/TiO₂) composite. The GO was synthesized by modified Hummers method and the composite is synthesized by chemical reflux method. The surface morphology of the composite was analyzed using a scanning electron microscope (SEM), and it is clearly observed that TiO₂ spheres are adsorbed on the surface of GO in a disordered manner.

An efficient new dual fluorescent pyrene based chemosensor for the detection of bismuth (III) and aluminium (III) ions and its applications in bio-imaging.

A new simple pyrene based schiff base chemosensor 1 (nicotinic acid pyren-1-ylmethylene-hydrazide) has been constructed and is prepared from 1-pyrenecarboxaldehyde and nicotinic hydrazide. Notably, the chemosensor 1 exhibited remarkable colour changes while in the presence of trivalent metal ions like Bi & Al ion in DMSO-HO, (1:1 v/v, HEPES = 50 mM, pH = 7.4).

Fluorenone based fluorescent probe for selective "turn-on" detection of pyrophosphate and alanine.

To sense biologically important entities with different size and dimensions, a fluorenone based fluorescent receptor was designed and synthesized. Probe 1 displayed a distinct fluorescence enhancement emission at 565nm for pyrophosphate and 530nm for alanine in polar solvent. The fluorescence titration experiments confirm 1:1 stoichiometric ratio with high-binding constant and very low limit of detection (LoD) values.