Publications by authors named "Nandan Anavekar"

Article Synopsis
  • AL amyloidosis can lead to heart issues (AL-CM), and existing imaging techniques struggle to identify heart dysfunction accurately.* -
  • A study involving cardiac MRIs compared patients with AL-CM to healthy individuals, revealing lower myocardial function index (MFI) in AL-CM patients and indicating MFI as a potential marker for risk assessment.* -
  • The findings showed that a lower MFI correlates with worse survival rates, making it a valuable tool for evaluating heart health in AL-CM patients.*
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Eosinophilic myocarditis (EM) is a rare cause of heart failure, with high in-hospital mortality associated with fulminant disease. A 61-year-old female transplant recipient was diagnosed with COVID-19 after presenting with 2 days of constitutional symptoms. She developed acute heart failure from EM.

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Coronary CT angiography (CCTA) is now endorsed by all major cardiology guidelines for the investigation of chest pain and assessment for coronary artery disease (CAD) in appropriately selected patients. CAD is a leading cause of morbidity and mortality. There is extensive literature to support CCTA diagnostic and prognostic value both for stable and acute symptoms.

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Background: Patients with acute heart failure (AHF) exacerbation are susceptible to complications in the setting of COVID-19 infection. Data regarding the racial/ethnic and sex disparities in patients with AHF and COVID-19 remains limited.

Objective: We aim to evaluate the impact of race, ethnicity, and sex on the in-hospital outcomes of AHF with COVID-19 infection using the data from the National Inpatient Sample (NIS).

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Article Synopsis
  • * Twelve patients were analyzed retrospectively, revealing that echocardiograms and other imaging methods identified issues like endocarditis, aortic root abscesses, and myocarditis in these individuals.
  • * Findings indicate that multimodal imaging is crucial for early diagnosis and management of such infections, aiding in quicker treatment decisions while laboratory results are still pending.
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As ECG technology rapidly evolves to improve patient care, accurate ECG interpretation will continue to be foundational for maintaining high clinical standards. Recent studies have exposed significant educational gaps, with many healthcare professionals lacking sufficient training and proficiency. Furthermore, integrating new software and hardware ECG technologies poses challenges about potential knowledge and skill erosion.

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Background: Outcomes of device-detected AF remain unclear in individuals without a prior history of AF.

Methods: A meta-analysis was conducted to evaluate outcomes in individuals with no prior history of AF who experienced device-detected AF. Outcomes assessed were clinical AF, thromboembolism and all-cause mortality.

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Article Synopsis
  • - The study analyzed outcomes of intravascular ultrasound (IVUS) versus non-IVUS in patients undergoing peripheral vascular intervention (PVI) using data from the National Readmission database between 2016 and 2019.
  • - It involved a large cohort (434,901 hospitalizations) and found no significant difference in major amputation rates at 6 months between both groups, with amputation rates being 2.17% for IVUS and 2.71% for non-IVUS.
  • - However, in specific subgroups, namely patients with rest pain, those receiving iliac interventions, or those with drug-eluting stents, IVUS use was associated with significantly lower major amputation rates.
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Introduction: Cardiology conferences represent a major avenue for learning, career advancement, and professional networking. Yet, costs of attending these conferences represent a major barrier, particularly for trainees and participants from low-middle-income countries (LMICs). Our study aimed to analyze the registration fees of major cardiology conferences worldwide.

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Inflammatory disease of the pericardium represents a relatively common presentation, especially among the young. For the most part, inflammatory pericardial disease can be expeditiously and effectively managed without significant sequelae. However, some individuals present with severe and recurrent illness, representing significant therapeutic challenges.

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Introduction: Apical hypertrophic cardiomyopathy (ApHCM) is a subtype of hypertrophic cardiomyopathy (HCM) that affects up to 25% of Asian patients and is not as well understood in non-Asian patients. Although ApHCM has been considered a more "benign" variant, it is associated with increased risk of atrial and ventricular arrhythmias, apical thrombi, stroke, and progressive heart failure. The occurrence of pulmonary hypertension (PH) in ApHCM, due to elevated pressures on the left side of the heart, has been documented.

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Limited data exist regarding outcomes after coronary angiography (CAG) and percutaneous coronary intervention (PCI) in patients aged ≥90 years admitted to the cardiac intensive care unit (CICU) with acute coronary syndrome (ACS). We studied sequential CICU patients ≥90 years admitted with ACS from 2007 to 2018. Three therapeutic approaches were defined: (1) No CAG; (2) CAG without PCI (CAG/No PCI); and (3) CAG with PCI (CAG/PCI).

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Article Synopsis
  • ECG interpretation skills among healthcare professionals are often lacking, creating a need for effective learning resources.
  • A study involving 1206 professionals tested the effectiveness of web-based training methods, with participants divided into four groups: question bank, lecture, hybrid, and control (no resources).
  • Results showed significant improvements in ECG interpretation among those using learning resources, with the question bank and hybrid groups performing especially well, while the control group saw minimal gains.
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Thoracic aortic aneurysm (TAA) is a commonly encountered disease that is defined as aortic dilation with an increase in diameter of at least 50% greater than the expected age- and sex-adjusted size. Thoracic aortic aneurysms are described by their size, location, morphology, and cause. Primary care clinicians and other noncardiologists are often the first point of contact for patients with TAA.

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Article Synopsis
  • The study aimed to explore the differences in cardiac function between patients classified as having shock or preshock by using a noninvasive method called transthoracic echocardiography (TTE).
  • Researchers analyzed data from 5,375 cardiac intensive care patients, categorizing them based on the presence of hypotension and hypoperfusion, finding that varying degrees of hemodynamic compromise were linked to differences in TTE findings.
  • The results indicated that patients with more severe cardiac dysfunction, as evidenced by TTE parameters, had higher in-hospital mortality rates, suggesting that combining clinical classifications with TTE assessments can effectively predict patient outcomes.
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