Publications by authors named "Nancy Xing"
forager: a Python package and web interface for modeling mental search.
Behav Res Methods
September 2024
Analyzing data from the verbal fluency task (e.g., "name all the animals you can in a minute") is of interest to both memory researchers and clinicians due to its broader implications for memory search and retrieval.
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- Angiogenesis, or the growth of new blood vessels, is important for maintaining balance in the brain, and previous studies showed increased angiogenesis markers in rats during recovery from alcohol dependence.
- Systemic injections of the angiogenesis inhibitor endostatin reduced the likelihood of relapse to drinking in female rats but not in males, and it did not affect relapse to sucrose drinking in either sex.
- Endostatin also affected various cellular processes in the prelimbic cortex, with distinct impacts on neuroimmune and synaptic changes between genders, suggesting a new approach to treating alcohol relapse, particularly in females.
Carbonic anhydrase (CA) is abundant in glial cells in the brain and CA type II isoform (CA II) activity in the hippocampus plays an important role in buffering extracellular pH transients produced by neural activity. Chronic ethanol exposure results in respiratory and metabolic acidosis, producing shifts in extracellular pH in the brain and body. These neurophysiological changes by ethanol are hypothesized to contribute to the continued drinking behavior and physical withdrawal behavior in subjects consuming ethanol chronically.
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