Publications by authors named "Nancy Weyns"

Current radiocesium (Cs) models to evaluate the risk of Cs transfer from soil to plants are based on the clay and exchangeable potassium (K) contents in soil. These models disregard the mineralogy of the clay fraction and are likely not capable of accurately predicting the Cs transfer factor (TF) in soils of contrasting parent rocks and weathering stages. The objectives of this study were to test that hypothesis and to identify whether quantitative information on mineralogy can improve the predictions.

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The zyxin family of proteins consists of five members, ajuba, LIMD1, LPP, TRIP6 and zyxin, which localize at cell adhesion sites and shuttle to the nucleus. Previously, we established that LPP interacts with the tumor suppressor Scrib, a member of the leucine-rich repeat and PDZ (LAP) family of proteins. Here, we demonstrate that Scrib also interacts with TRIP6, but not with zyxin, ajuba, or LIMD1.

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For the currently used (99m)Tc-labeled diphosphonates such as (99m)Tc-MDP and (99m)Tc-HDP, the required interval of 2.5 to 3 h between injection and the scintigraphic bone imaging is an inconvenience. The present study was set up in an attempt to develop a technetium-99m-labeled diphosphonate with efficient bone uptake and more rapid clearance from blood and soft tissue by renal extraction and excretion so that it would be possible to start imaging as early as 1 h after injection.

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