Protective effects of a chemically characterized extract from leaves on acetaminophen-induced liver injury.

Distinct parts of Swartz. (Solanaceae) are popularly used for a variety of therapeutic purposes. This study determined the phytochemical composition of a phenolic fraction of leaf aqueous extract and investigated its antioxidant and liver-protective properties.

Chemical profile, liver protective effects and analgesic properties of a Solanum paniculatum leaf extract.

Background/aim: Solanum paniculatum L. (Solanaceae) is a plant native to South America where it is used in traditional medicine for different therapeutic indications. This study evaluated the chemical composition and the hepatoprotective and analgesic activities of S.

Toxicological evaluation of an ethanolic extract from Chiococca alba roots.

The roots of Chiococca alba have been employed to treat rheumatic disorders and for other therapeutic purposes in Brazil and elsewhere. This study was undertaken to evaluate the toxicological properties of an ethanolic extract from Chiococca alba roots (EE), including mutagenicity in the Salmonella assay and acute and subacute toxicity to mice. Single oral doses of EE caused hypoactivity, but no deaths were noted up to the highest dose tested (2000 mg/kg).