Antifungal activity against planktonic and biofilm Candida albicans in an experimental model of foreign-body infection.

Objectives: The treatment of Candida implant-associated infections remains challenging. We investigated the antifungal activity against planktonic and biofilm Candida albicans in a foreign-body infection model.

Methods: Teflon cages were subcutaneously implanted in guinea pigs, infected with C.