A pilot study to test the practicality and efficiency of methods used to evaluate colon cleansing in an inpatient setting.

The purpose of the study was to test measurement methods in an inpatient setting for future use in a multisite study about bowel cleansing before colonoscopy. Because the multisite study used data collectors at distant geographic points who might have limited time to devote to data collection, the forms needed to be tested for practicality and efficiency. The data collection procedures worked well, but we experienced unexpected difficulties recruiting inpatients.

Efficacy of omega-3 fatty acids in children and adults with IgA nephropathy is dosage- and size-dependent.

Previous studies that have evaluated fish oil preparations in patients with IgA nephropathy (IgAN) have produced a wide range of conclusions. Proposed explanations for these discordant results have not provided a unifying hypothesis. Results from two clinical trials were analyzed to examine whether there is a dosage-dependent effect of Omacor, a purified preparation of omega-3 fatty acids, in patients with IgAN.

Clinical trial to evaluate omega-3 fatty acids and alternate day prednisone in patients with IgA nephropathy: report from the Southwest Pediatric Nephrology Study Group.

This randomized, placebo-controlled, double-blind trial evaluated the role of prednisone and omega 3 fatty acids (O3FA) in patients with IgA nephropathy. Entry criteria were (1) biopsy-proven IgA nephropathy, (2) estimated GFR > or = 50 ml/min per 1.73 m2, and (3) moderate to severe proteinuria.