Publications by authors named "Nancy Nalleweg"
Article Synopsis
- IL-9 plays a significant role in ulcerative colitis (UC), showing increased expression in inflamed tissue compared to healthy controls.
- The study found that CD3(+) T cells are the main source of IL-9, which also affects other immune cells like polymorphonuclear leucocytes (PMN) and promotes pro-inflammatory responses.
- Targeting IL-9 could offer a new therapeutic strategy for managing UC, as it significantly influences gut inflammation and epithelial cell functions.
Erbin, a binding partner of ErbB2, was identified as the first member of the LAP family of proteins. Erbin was shown at postsynaptic membranes of the neuromuscular junction (NMJ) or in cultured C2C12 myotubes (1) to be concentrated, (2) to regulate the Ras-Raf-Mek pathway, and (3) to inhibit TGF-beta signaling. In the CNS, Erbin interacts with PSD-95.
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