Publications by authors named "Nancy Karreman"
Despite evidence that dietary population health interventions are effective and widely accepted, they remain the topic of intense debate centring on the appropriate role of the state. This review sought to identify how the role of the state in intervening in individuals' food practices is conceptualized across a wide range of literatures. We searched 10 databases and 4 journals for texts that debated dietary population health interventions designed to affect individuals' health-affecting food practices.
View Article and Find Full Text PDFSome tobacco companies claim they are 'transforming' by adopting harm reduction goals or even seeking to achieve a 'smokefree' world. What characterises transformation and whether companies can or are transforming is unclear. Nevertheless, such claims are gaining traction.
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- The DUX4 transcription factor is essential for early embryonic development but becomes toxic when misexpressed in skeletal muscle, leading to facioscapulohumeral muscular dystrophy (FSHD).
- The study identifies that DUX4-induced toxicity involves the production of double-stranded RNAs (dsRNAs) that come from specific genomic elements like inverted Alu repeats and human satellite II (HSATII) repeats.
- Findings reveal that DUX4 triggers the transcription of HSATII repeats in muscle cells, which contributes to cell death, highlighting the role of these dsRNAs in the pathology of FSHD.