Publications by authors named "Nancy Jabbour"
Regulatory small RNAs (sRNAs) are involved in the adaptation of bacteria to their environment. CiaR-dependent sRNAs (csRNAs) are controlled by the regulatory two-component system (TCS) CiaRH, which is widely conserved in streptococci. Except for Streptococcus pneumoniae and Streptococcus sanguinis, the targets of these csRNAs have not yet been investigated.
View Article and Find Full Text PDFArticle Synopsis
- Bacteria use complex regulatory networks, starting with transcriptional control through mechanisms like two-component systems (TCSs), to adapt to changing environments and survive stress.
- The CiaRH TCS is particularly important for certain streptococcal species, playing a critical role in their survival and pathogenesis.
- The review explores how csRNAs, regulated by CiaRH, contribute to bacterial adaptation and virulence, emphasizing their significance in the overall survival strategy of these opportunistic pathogens.