Synopsis of recent research by authors named "Nancy J Grant"
- Nancy J Grant's research primarily focuses on the mechanisms of phagocytosis and the role of phospholipase D (PLD) and phosphatidic acid (PA) in immune responses, particularly in macrophages, highlighting the importance of small GTPases like Arf6 and Ral in these processes
- Additionally, her studies on prion diseases explore the cerebellar pathology associated with different prion strains, emphasizing the specific histopathological alterations caused by distinct prion proteins and their effects on neuronal health
- Grant's work also delves into cellular signaling mechanisms, examining how phospholipid scramblase and autophagy are involved in phagocytosis and neuronal cell death, which provides insight into potential therapeutic targets for neurodegenerative diseases.
