Publications by authors named "Nancy Gullet"
Article Synopsis
- Electronic Health Record (EHR) systems are essential digital tools in clinical practice that store patient health information and can enhance research studies, particularly platform trials, which utilize multiple treatment options under one protocol.
- Despite their potential, challenges like incomplete records and complex eligibility criteria must be addressed for effective use of EHRs in research.
- The EU-PEARL project aims to develop methods and tools for better assessing EHR protocol feasibility, selecting clinical sites, and efficiently pre-screening patients for platform trials, using a consensus-based readiness survey and interoperable queries.
Background: In individuals at clinical high-risk for psychosis, elevated cortisol levels predict subsequent onset of psychotic disorder. However, it is unclear whether cortisol alterations are evident at an earlier clinical stage and promote progression of psychosis expression. This study aimed to address this issue by investigating whether cortisol levels in childhood were associated with the emergence of attenuated psychotic symptoms in early adulthood.
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