Enhancing creative divergent thinking in older adults with a semantic retrieval strategy.

Creative divergent thinking involves the generation of unique ideas by pulling from semantic memory stores and exercising cognitive flexibility to shape these memories into something new. Although cognitive abilities decline with age, semantic memory tends to remain intact. This study aims to utilize that memory to investigate the effectiveness of a brief cognitive training to improve creative divergent thinking.

Examining the neural basis of unitization: A review.

Associative memory refers to the ability to form and remember associations between individual pieces of information rather than memory for a single object or word. Encoding associations in memory tends to be a more difficult task than item (only) encoding, because associative memory requires encoding multiple items as well as the specific links amongst the items. Accordingly, researchers have worked to identify interventions and strategies to reduce the effort and neural resources required for successful associative memory processing.

Investigating the neural basis of schematic false memories by examining schematic and lure pattern similarity.

Schemas allow us to make assumptions about the world based upon previous experiences and aid in memory organisation and retrieval. However, a reliance on schemas may also result in increased false memories to schematically related lures. Prior neuroimaging work has linked schematic processing in memory tasks to activity in prefrontal, visual, and temporal regions.

Investigating the neural basis of schematic false memories by examining schematic and lure pattern similarity.

Schemas allow us to make assumptions about the world based upon previous experiences and aid in memory organization and retrieval. However, a reliance on schemas may also result in increased false memories to schematically related lures. Prior neuroimaging work has linked schematic processing in memory tasks to activity in prefrontal, visual, and temporal regions.

Memory and creativity: A meta-analytic examination of the relationship between memory systems and creative cognition.

Increasing evidence suggests that specific memory systems (e.g., semantic vs.

Does unitization really function like items? The role of interference on item and associative memory processes.

Associative memory declines as we age, while item memory remains relatively stable. Previous work has shown that, in both younger and older adults, while item recognition declines linearly across time and interference, associative recognition declines only with longer delays and more interference. Unitization is a memory process found to support associative memory by allowing pairs to presumably be processed like single items.

Age-related differences in encoding-retrieval similarity and their relationship to false memory.

Typical aging is associated with increases in false memory rates among older adults. Such errors are frequently associated with differential neural activity during encoding and retrieval in older compared to younger adults within visual cortices and the hippocampus. It remains unknown how pattern similarity reductions relate to false memories in healthy aging.

Understanding associative false memories in aging using multivariate analyses.

Age-related declines in associative memory are ubiquitous, with decreases in behavioral discriminability largely arising from increases in false memories for recombined lures. Using representational similarity analyses to examine the neural basis of associative false memories in aging, the current study found that neural pattern similarity between Hits and FAs and Hits and CRs differed as a function of age in occipital ROIs, such that older adults exhibited a smaller difference between the two similarity metrics than did younger adults. Additionally, greater Hit-FA representational similarity correlated with increases in associative FAs across several ROIs.

The effect of memory cue duration on performance in the directed forgetting task in healthy aging.

Although forgetting is usually considered a memory error, intentional forgetting can function as an adaptive mechanism. The current study examined the effect of increased processing time on directed forgetting in aging as a mechanism to compensate for age-related forgetting. Specifically, an item-method directed forgetting paradigm was used in conjunction with Remember/Know/New responding to examine the effect of cue duration (1, 3, 5 s) on directed forgetting and remembering in younger and older adults.

The influence of item familiarization on neural discriminability during associative memory encoding and retrieval.

Associative memory requires one to encode and form memory representations not just for individual items, but for the association or link between those items. Past work has suggested that associative memory is facilitated when individual items are familiar rather than simultaneously learning the items and their associative link. The current study employed multivoxel pattern analyses (MVPA) to investigate whether item familiarization prior to associative encoding affects the distinctiveness of neural patterns, and whether that distinctiveness is also present during associative retrieval.

Fornix white matter microstructure differentially predicts false recollection rates in older and younger adults.

Healthy aging is accompanied by increased false remembering in addition to reduced successful remembering in older adults. Neuroimaging studies implicate age-related differences in the involvement of medial temporal lobe and fronto-parietal regions in mediating highly confident false recollection. However, no studies have directly examined the relationship between white matter microstructure and false recollection in younger and older adults.

Examining the Neural Basis of Congruent and Incongruent Configural Contexts during Associative Retrieval.

Disrupting the configural context, or relative organization and orientation of paired stimuli, between encoding and retrieval negatively impacts memory. Using univariate and multivariate fMRI analyses, we examined the effect of retaining and manipulating the configural context on neural mechanisms supporting associative retrieval. Behavioral results showed participants had significantly higher hit rates for recollecting pairs in a contextually congruent, versus incongruent, configuration.

Cross-situational statistical learning in younger and older adults.

Research investigating statistical learning, the process of tracking regularities in the environment, in older adults has been limited; with existing studies suggesting there are age-related declines. We aim to further understand older adults' statistical learning abilities using a cross-situational statistical learning paradigm in which learners map novel words to novel objects. In Experiment 1, we manipulated task difficulty and found an overall age deficit but no interaction between age and difficulty.

Lexical frequency affects functional activation and accuracy in picture naming among older and younger adults.

As individuals age, they experience increased difficulties producing speech, especially with infrequent words. Older adults report that word retrieval difficulties frequently occur and are highly frustrating. However, little is known about how age affects the neural basis of language production.

Shared neural recruitment across working memory and motor control tasks as a function of task difficulty and age.

Past research suggests that working memory (WM) and motor control may engage similar cognitive and neural mechanisms in older adults, particularly when task difficulty increases. However, much of this evidence arises from comparisons across behavioral and imaging studies that test only one of the foregoing functional domains. The current study used fMRI within the same group of older adults to investigate whether WM and motor control recruit common mechanisms, and whether recruitment increased with task demand and age.

Different types of associative encoding evoke differential processing in both younger and older adults: Evidence from univariate and multivariate analyses.

Age-related deficits in associative processing are well-documented (e.g., Naveh-Benjamin, 2000) and have been assumed to be the result of a general deficit that affects all types of binding.

Memory for the usual: the influence of schemas on memory for non-schematic information in younger and older adults.

Schemas are abstract mental representations that influence perceptual and memory processes. Schemas can aide memory for information that is related or congruent with a given schema (i.e.

Sensory Representations Supporting Memory Specificity: Age Effects on Behavioral and Neural Discriminability.

Older adults' difficulty in distinguishing between old and new information contributes to memory decline, which may occur because older adults are less likely than young adults to retrieve specific sensory details necessary to distinguish between similar items. In male and female human subjects, the present study measured the extent of age differences in the specificity of memory representations using a false memory paradigm in which studied items were linked to retrieval items at multiple levels of similarity. Older adults showed poorer behavioral discrimination than young adults, driven primarily by false recognition of lures that differed from targets only in perceptual details.

The Effects of Useful Field of View Training on Brain Activity and Connectivity.

Objectives: Useful Field of View training (UFOVt) is an adaptive computerized cognitive intervention that improves visual attention and transfers to maintained health and everyday functioning in older adults. Although its efficacy is well established, the neural mechanisms underlying this intervention are unknown. This pilot study used functional MRI (fMRI) to explore neural changes following UFOVt.

Using attribute amnesia to test the limits of hyper-binding and associative deficits in working memory.

Previous work has shown mixed evidence regarding age-related deficits for binding in working memory. The current study used the newly developed attribute amnesia effect (H. Chen & Wyble, 2015a) to test the associative-deficit hypothesis during working memory and to probe whether hyper-binding extends to include binding of de-selected information.

Older adults' associative memory is modified by manner of presentation at encoding and retrieval.

Relative to young adults, older adults typically exhibit a reduced ability to accurately remember associations between stimuli. Prior research has assumed that this age-related memory impairment affects different types of associations similarly. However, research in young adults has suggested that item-item and item-context associations are supported by different underlying neural mechanisms that could be unequally affected by aging.

Differentiating True and False Schematic Memories in Older Adults.

Objective: While schemas aid memory for schematically related information, the gist induced by the schema can also lead to high rates of false memories, especially in older adults. The neural mechanisms that support and differentiate true and false memories in aging are not well understood. The current study sought to clarify this, using a novel scene paradigm to investigate the role of schemas on true and false memories in older adults.

The influence of perceptual similarity and individual differences on false memories in aging.

Previous false memory research has suggested that older adults' false memories are based on an overreliance on gist processing in the absence of item-specific details. Yet, false memory studies have rarely taken into consideration the precise role of item-item similarity on the cognitive and neural mechanisms underlying perceptual false memories in older adults. In addition, work in our laboratory has suggested that when investigating the neural basis of false memories in older adults, it is equally as critical to take into account interindividual variability in behavior.