Copper(II) and zinc(II) complexation with -ethylene hydroxycyclams and consequences on the macrocyclic backbone configuration.

We report a series of four cyclams and cross-bridged cyclams, -functionalized by one hydroxyethyl arm, which may incorporate additional methyl(s) group(s). The Cu(II) and Zn(II) complexes of these ligands were synthesized and fully characterized. The investigation of the metal complexes in solid-state and in solution was carried X-ray diffraction, NMR, EPR, absorption spectroscopy and DFT calculations.

Application of Doehlert experimental design for the removal of radium from aqueous solution by cross-linked phenoxycalix[4]pyrrole-polymer using Ba(II) as a model.

Ra-226 is a naturally occurring radionuclide that is derived from uranium-238 series, and it is present at low concentrations in rocks, soil, and groundwater. Many efforts have been exerted for the decontamination of radium from aqueous media in order to meet the increasing water demand of the population. To this aim, a new polymer based on cross-linked phenoxycalix[4]pyrrole was designed and employed in solid/liquid extractions in order to remove radium from aqueous solutions.

Solid-liquid extraction of iodide and bromide from aqueous media by a new water-insoluble phenoxycalix[4]pyrrole-epichlorohydrin polymer.

The present study describes the synthesis of the first phenoxycalix[4]pyrrole-epichlorohydrin based polymer. The advantage of the latter resides in its fast-single step synthesis protocol, low cost, water insolubility and its unexpected anion extraction capacity. The study of this polymer by various solid/liquid extractions with halides in aqueous solutions and quantitative ion chromatography analysis showed that unlike other calix[4]pyrrole-based entities, this polymer extracts iodide rather than bromide and fluoride owing to the presence of large extraction pockets.

A click mediated route to a novel fluorescent pyridino-extended calix[4]pyrrole sensor: synthesis and binding studies.

A novel fluorescent aryl-extended phenoxycalix[4]pyrrole ditopic sensor with enhanced cation recognition properties was efficiently synthesized via click chemistry and characterized through both molecular fluorescence and nuclear magnetic resonance spectroscopy. Results demonstrate the selectivity of this fluorescent sensor for fluoride when taking into account its interaction with anions, while its cation binding properties showed selectivity for iron, and its sensing properties for several cations in dimethylsulfoxide. This work introduces a new ditopic receptor able to complex major environmentally relevant species and depicts the importance of click chemistry in the introduction of new tetra-chromophoric calix[4]pyrrole binding platforms with specific photophysical properties.