Effect of conditioning intensity on late complications in AYA who underwent allogeneic HCT during childhood.

We retrospectively analyzed the effect of conditioning intensity on 22 late complications in 145 adolescent and young adults who underwent allogeneic hematopoietic cell transplantation (HCT) in childhood. Seventy-six patients received myeloablative conditioning (MAC), while 69 received reduced-intensity conditioning (RIC). Incidence rates of late complications (≥ 1), organ dysfunction, endocrine/metabolic abnormalities, and psychosocial issues in evaluable patients were 71.