Publications by authors named "Nanami Saito"
Background: Axolotls have remarkable organ-level regeneration capability. They can regenerate their limbs, tail, brain, gills, and heart. The liver had been considered to be a regenerative organ in these highly regeneration-competent animals.
View Article and Find Full Text PDFThe presence of nerves is an important factor in successful organ regeneration in amphibians. The Mexican salamander, Ambystoma mexicanum, is able to regenerate limbs, tail, and gills when nerves are present. However, the nerve-dependency of tooth regeneration has not been evaluated.
View Article and Find Full Text PDFGill regeneration has not been well studied compared to regeneration of other appendages, such as limb and tail regeneration. Here, we focused on axolotl gill regeneration and found that Fgf- and Bmp-signaling are involved in their gill regeneration mechanism. Axolotls have three pairs of gill rami, and each gill ramus has multiple gill filaments.
View Article and Find Full Text PDFArticle Synopsis
- Limb regeneration in Xenopus laevis involves reactivating developmental processes, similar to forming a limb bud in adults, which is significant for understanding how mature organisms can regenerate limbs.
- The study focused on the re-expression of the larval gene krt62.L during limb regeneration in froglets, indicating a connection between larval and adult developmental stages.
- Nerve factors play a key role in maintaining krt62.L expression during limb regeneration, and experiments show that krt62.L-positive tissues can support limb development even in an adult froglet context.