Publications by authors named "Nana Tetruashvili"
Article Synopsis
- Umbilical cord blood's use in hemostasis testing for newborns is under-researched, leading to this study aimed at evaluating its applicability compared to venous blood samples.
- The study involved 187 newborns and found that umbilical cord blood exhibited a hypocoagulable shift in clotting times and fibrinogen levels, while thromboelastometry and thrombodynamics showed a hypercoagulable shift in newborn blood.
- The differences in hemostatic parameters highlight that newborns have distinct coagulation profiles compared to adults, with implications for understanding their physiological and pathological hemostatic features.
Pregnancy loss can be defined as a loss before either 20 or 24 weeks of gestation (based on the first day of the last menstrual period) or the loss of an embryo or fetus less than 400 g in weight if the gestation age is unknown. Approximately 23 million pregnancy losses occur worldwide every year, equating to 15-20% of all clinically recognized pregnancies. A pregnancy loss is usually associated with physical consequences, such as early pregnancy bleeding ranging in severity from spotting to hemorrhage.
View Article and Find Full Text PDFProblem: We hypothesized that expression of transmembrane glycoprotein CD200 on paternal lymphocytes used for pre-gestational lymphocyte immunotherapy (LIT) of recurrent spontaneous abortion (RSA) can suppress the pro-inflammatory Th1-type immunity required for successful implantation. To reveal the association between CD200 expression, female immune background after LIT, and pregnancy establishment, we have performed this work.
Method Of Study: Pre-gestational alloimmunizations were given to 37 women using paternal peripheral blood leukocytes, combined with additional alloimmunizations in case of pregnancy.
Objectives: The aim of this study was to establish maternal contribution to false positive noninvasive prenatal DNA screening (NIPS) results and develop the method to distinguish maternal and fetal origin of high-risk monosomy X NIPS calls including mosaic maternal cases.
Method: A total of 906 women carrying singleton pregnancies have been recruited. Maternal plasma DNA semiconductor massive parallel sequencing was performed to detect common aneuploidies.