High prevalence of antibiotic resistance in commensal Escherichia coli from healthy human sources in community settings.

Antibiotic resistance is a global health crisis that requires urgent action to stop its spread. To counteract the spread of antibiotic resistance, we must improve our understanding of the origin and spread of resistant bacteria in both community and healthcare settings. Unfortunately, little attention is being given to contain the spread of antibiotic resistance in community settings (i.

Prevalence of multidrug-, extensive drug-, and pandrug-resistant commensal isolated from healthy humans in community settings in low- and middle-income countries: a systematic review and meta-analysis.

Background: The majority of existing studies aimed at investigating the incidence and prevalence of multidrug-resistance by bacteria have been performed in healthcare settings. Relatively few studies have been conducted in community settings, but these have consistently shown a high prevalence of multidrug-resistant bacteria in low- and middle-income countries (LMICs).

Objectives: To provide an appraisal of the evidence on the high prevalence of multidrug-, extensive drug-, and pandrug-resistance in commensal isolates from human sources in community settings in LMICs.