Aim: To investigate the clinical and pathological significance of altered retinoblastoma (Rb) encoding protein (pRb) in gastric carcinoma.
Methods: Expression of altered pRb was analyzed in 91 patients with gastric adenocarcinoma by immunohistochemistry.
Results: Sixty-five percent (59/91) of the tumors were positively stained and the staining in tumor nuclei of gastric carcinoma ranged 0%-90%.