Antitumor effects of saikosaponin b2 on breast cancer cell proliferation and migration.

Saikosaponin b2 (SSb2) can be extracted from Bupleurum spp. roots (Radix Bupleuri), which belongs to the Umbelliferae family. The current study aimed to explore the effects of SSb2 on proliferation of breast cancer cells and to identify the mechanism by which SSb2 affects breast cancer cell migration.

The effects of celecoxib on the proliferation and ultrastructural changes of MDA-MB-231 breast cancer cells.

This study sought to investigate the effects of celecoxib on the proliferation and morphological changes of triple-negative breast cancer (TNBC) MDA-MB-231 cells. In this study, after MDA-MB-231 cells were treated with a certain concentration of celecoxib, a cell counting kit-8 (CCK-8) proliferation assay was used to detect cell viability. Western blotting was utilized to analyze the expression level of caspase-3, which is an apoptosis-related protein.

[Study on Chemical Constituents of Lonicera japonica Bud].

Objective: To study the chemical constituents of Lonicera japonica bud.

Methods: The compounds were isolated and repeatedly purified by silica gel column chromatography, gel column chromatography and ODS chromatography. The structures were elucidated by physicochemical properties, MS and NMR.