Fabrication of a chitosan/bioglass three-dimensional porous scaffold for bone tissue engineering applications.

Bone defects caused by trauma and disease have become urgent problems. Three-dimensional (3D) porous scaffolds for bone tissue engineering should ideally have an interconnected porous structure, good biocompatibility and mechanical properties similar to those of natural bones. In the present study, a chitosan/bioglass (CS/BG) 3D porous scaffold was constructed by initially preparing a CS fibre 3D porous scaffold by needle-punching, and then depositing BG on the scaffold by dip-coating.