Publications by authors named "Nan-Du Luo"

Objective: To explore the clinical correlation and prognostic value of the Albumin-Bilirubin (ALBI) score in children with secondary hemophagocytic syndrome(sHLH).

Methods: A retrospective analysis was conducted on the data of children's sHLH cases clearly diagnosed in the Affiliated Hospital of Zunyi Medical University from January 2012 to March 2023. Survival analysis was conducted according to the ALBI classification.

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Article Synopsis
  • The study analyzed 73 children diagnosed with hemophagocytic syndrome (HLH) and categorized them based on their Epstein-Barr virus (EBV) DNA levels into three groups: negative, low load, and high load.
  • Results showed that children in the high load group had more severe clinical symptoms and complications, including higher rates of liver and spleen swelling, blood involvement, and disseminated intravascular coagulation (DIC) compared to the other groups.
  • The researchers concluded that higher EBV DNA loads were linked to worse prognosis, observed through various laboratory indicators and their correlation with the severity of organ involvement in children with HLH.
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