Comparison of dosimetric parameters for predicting radiation-induced cataract in paediatric patients.

Introduction: This study compared the predictive ability of radiation-induced cataract between maximum point dose of the lens (Lens Dmax) ≥7 Gy, mean lens dose (Lens Dmean) ≥7 Gy, Lens Dmax ≥10 Gy, and Lens Dmean ≥10 Gy.

Methods: Patients aged 3-18 years received cranial irradiation or radiation therapy at head and neck area between January 2010 and December 2019 at our institute were included. Patients without baseline and/or follow-up eye examination were excluded.

Effects of Radiation Therapy on Immunological and Virological Status in HIV-Infected Cancer Patients in Thailand: A Multicenter Prospective Study.

Background: Radiation therapy (RT) is the core part of cancer multidisciplinary management which causes myelosuppression. The current standard or RT among HIV-positive cancer patients who are immuno-compromised does not differ from that of HIV-negative ones.

Objective: To determine the effects of radiation therapy on immunological and virological status among HIV-infected cancer patients.

Effect of radiation therapy to immunological and virological status in HIV/AIDS-cancer patients, preliminary report.

Objective: To describe effects of radiation therapy (RT) on immunological status (CD4 cell counts) and disease progression among HIV-positive cancer patients.

Material And Method: This prospective observational study was conducted among HIV-positive cancer patients who received RT for curative intention of cancer in five selected hospitals in Thailand. All subjects received external beam radiation therapy, according to standard clinical practice guidelines of RT.

The effectiveness of clinical practice guideline for nasopharyngeal and oropharyngeal cancer to reduce acute treatment toxicity from concurrent chemoradiation.

Objective: To evaluate the effectiveness of clinical practice guideline (CPG) for nasopharyngeal carcinoma (NPC) and oropharyngeal carcinoma (OPC) on reducing acute toxicity during concurrent chemoradiation (CRT).

Material And Method: The prospective study enrolled 74 patients diagnosed of NPC and OPC that underwent concurrent CRT. The feasibility of CPG was evaluated.

Effect of Amifostine to prevent radiotherapy-induced acute and late toxicity in head and neck cancer patients who had normal or mild impaired salivary gland function.

Background: Amifostine has a potential role for salivary gland protection in head and neck cancer patients who had radiotherapy.

Material And Method: Sixty-seven head and neck cancer patients were randomized to receive radiotherapy or radiotherapy plus Amifostine. The efficacy of the treatment was determined by a questionnaire evaluating dryness of mouth and the oral comfort, the RTOG/EORTC acute/late radiation morbidity scoring criteria, collection of the whole saliva and the 99mTc-pertecnetate scintigraphy of the salivary glands.

A randomized phase III trial of concurrent chemoradiotherapy in locally advanced cervical cancer: preliminary results.

Objective: Concurrent chemoradiation is the standard treatment for locally advanced cervical cancer. This study was a preliminary result of a randomized two arms, prospective, open-label phase III trial comparing the activity and safety of the concurrent chemoradiation of Tegafur-Uracil and carboplatin or carboplatin alone in locally advanced cervical cancer.

Materials And Methods: The stage IIB-IIIB cervical cancer patients were randomized to have Tegafur-Uracil 225 mg/m(2)/day orally, 5 days a week and carboplatin 100 mg/m(2) IV over 30-60 min, weekly on day 1 concurrent with standard radiotherapy (Group A) or carboplatin alone concurrent with standard radiotherapy (Group B).

Concurrent radiation therapy and irinotecan in stage IIIB cervical cancer.

Unlabelled: The present study was to evaluate the efficacy and toxicity of concurrent radiation therapy and irinotecan in patients with stage IIIB cervical cancer. Fifteen patients with no prior radiation therapy and chemotherapy were enrolled in the study. These patients received 50 Gy of external radiation to whole the pelvis, 50 Gy with an additional dose of 6-10 Gy to the parametrium and 1 or 2 sessions of intracavitary Cesium-137.