Chemosensory protein 22 in Riptortus pedestris is involved in the recognition of three soybean volatiles.

Riptortus pedestris (Hemiptera: Alydidae), a common agricultural pest, is the major causative agent of "soybean staygreen." However, the interactions between chemosensory proteins (CSPs) in R. pedestris and host plant volatiles have yet to be comprehensively studied.

Identification of attractants for adult Spodoptera litura based on the interaction between odorant-binding protein 34 and host volatiles.

Odorant-binding proteins (OBPs) play key roles in host plant location by insects, and can accordingly serve as important targets for the development of attractants. In this study, we detected the high expression of SlitOBP34 in male antennae of Spodoptera litura. Subsequently, the fluorescence competitive binding experiments displayed that the SlitOBP34 protein has binding affinity for different ligands.

Collision-free automatic berthing of maritime autonomous surface ships via safety-certified active disturbance rejection control.

This paper addresses the automatic berthing of a maritime autonomous surface ship operating in a confined water environment subject to static obstacles, dynamic obstacles, thruster constraints, and space constraints due to shorelines. A safety-certified active disturbance rejection control (ADRC) method is proposed for achieving the automatic berthing task of an MASS in the presence of model uncertainties and ocean disturbances. An extended state observer (ESO) based on a second-order robust exact differentiator (RED) is employed to estimate an extended state vector consisting of internal model uncertainties and external ocean disturbances.

The mechanism of lncRNA MALAT1 targeting the miR-124-3p/IGF2BP1 axis to regulate osteogenic differentiation of periodontal ligament stem cells.

Objectives: This study aimed to investigate the regulatory roles of lncRNA MALAT1, miR-124-3p, and IGF2BP1 in osteogenic differentiation of periodontal ligament stem cells (PDLSCs).

Materials And Methods: We characterized PDLSCs by employing quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot analyses to evaluate the expression of key osteogenic markers including ALPL, SPP1, and RUNX2. Manipulation of lncRNA MALAT1 and miR-124-3p expression levels was achieved through transfection techniques.

Exploring wound management in dental pulp: Utilizing single-cell RNA sequencing for global transcriptomic analysis in healthy and inflamed pulpal tissues.

The process of wound healing in the dental pulp is characterized by intricate interplay of signalling cascades, cellular responses, and extracellular matrix (ECM). The objective of this research was to examine the intricate interaction between signalling cascades, cellular responses, and extracellular matrix (ECM) dynamics that comprise the wound healing process of dental pulp. We conducted a controlled laboratory analysis of transcriptomic landscape of dental pulp tissues, including both healthy and inflamed samples, utilizing single-cell RNA sequencing.

Loss of Muscle Mass in Delayed Diagnosis of Renal Cysts and Diabetes Syndrome: A Case Report.

Renal cysts and diabetes syndrome (RCAD) is a rare disease caused by abnormalities in the HNF1B gene, which often leads to dysfunction in the renal, genital tracts, and pancreas. In this report, we present a rare case of a 27-year-old female with muscle mass loss who experienced a delayed diagnosis of RCAD. The patient had been misdiagnosed as "type 1 diabetes" for a long period.

Screening of behaviorally active compounds based on the interaction between two chemosensory proteins and mung bean volatiles in Callosobruchus chinensis.

Chemosensory proteins (CSPs) are involved in the earliest steps of the olfactory process by binding and transporting odorants and play a crucial role in the insect's search for food and egg-laying sites. In the present study, the tissue expression profiles showed that both CchiCSP3 and CchiCSP5 of Callosobruchus chinensis were highly expressed in the adult antennae. Subsequently, the recombinant CchiCSP3 and CchiCSP5 proteins were analysed using fluorescence competitive binding assays, and both showed binding affinities for the three mung bean volatiles.

Case report: mitochondrial diabetes mellitus in a Chinese family due to m.3243A>G.

Objectives: Mitochondrial diabetes mellitus is caused by dysfunctional mitochondria and is often misdiagnosed because of its various clinical manifestations. It's even rarer in children, and without a clear family history of diabetes with hearing loss, it's often difficult to diagnose.

Case Presentation: This is a case study of a family with maternally inherited diabetes mellitus and deafness (MIDD).

The establishment and validation of a prediction model for traumatic intracranial injury patients: a reliable nomogram.

Objective: Traumatic brain injury (TBI) leads to death and disability. This study developed an effective prognostic nomogram for assessing the risk factors for TBI mortality.

Method: Data were extracted from an online database called "Multiparameter Intelligent Monitoring in Intensive Care IV" (MIMIC IV).

Ligand-binding properties of chemosensory protein 1 in Callosobruchus chinensis to mung bean volatiles.

Callosobruchus chinensis (Coleoptera: Fabaceae) is a worldwide pest that feeds exclusively on legumes, and is the most serious pest affecting mung beans. Usually, the insect olfactory system plays a predominant role in searching for host plants and egg-laying locations. Chemosensory proteins (CSPs), are mainly responsible for transporting specific odour molecules from the environment.

Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity.

Microglia are highly dynamic immune cells of the central nervous system (CNS). Microglial processes interact with neuronal elements constantly on the order of minutes. The functional significance of this acute microglia-neuron interaction and its potential role in the context of pain is still largely unknown.

Collateral circulation detected by arterial spin labeling predicts outcome in acute ischemic stroke.

Background: Robust collateral circulation is strongly associated with good outcomes in acute ischemic stroke (AIS).

Aims: To determine whether collateral circulation detected by arterial spin labeling (ASL) magnetic resonance imaging could predict good clinical outcome in AIS patients with 90 days follow-up.

Materials And Methods: Total 58 AIS patients with anterior circulation stroke were recruited.

Application of Multiple Regression Analysis Model in Table Tennis Competition.

Since the table tennis mixed doubles competition was officially listed as the Olympic Games, the players around the world paid more attention to the project. In this background, the 20 mixed doubles finals were used in the literature, video observation, and analysis of multiple regression. From the receiving point of view, the score difference between men and women is not very great, but female players may be more consistent.

[Influence of the coronavirus disease 2019 pandemic on maternal breastfeeding for very low birth weight infants].

Objectives: To investigate the changes in the rate and volume of mother's own milk (MOM) feeding for very low birth weight infants (VLBWIs) hospitalized during the prevention and control of the coronavirus disease 2019 (COVID-19) pandemic.

Methods: A retrospective analysis was performed on the medical data of the VLBWIs with a gestational age of <32 weeks who were born and admitted to the Neonatal Intensive Care Unit of Nanjing Maternal and Child Health Hospital from January 2019 to December 2020. The changes in the rate and volume of MOM feeding for VLBWIs during hospitalization were examined.

The superior response speed of table tennis players is associated with proactive inhibitory control.

Objective: To explore the mechanism behind the faster volitional reaction time (RT) of open skill sports athletes from the perspective of proactive inhibitory control, with the hypothesis that the superior response speed of athletes from open skill sports is related to their enhanced capacity for releasing inhibition.

Methods: Participants were divided into two groups, an experimental group of 27 table tennis players and a control group of 27 non-athletes. By manipulating cue-target onset asynchrony (CTOA) in a simple cue-target detection task, the timing of target presentation occurred in different phases of the disinhibition process.

Association of Sirtuin 1 Gene Polymorphisms with the Risk of Coronary Heart Disease in Chinese Han Patients with Type 2 Diabetes Mellitus.

Aims: To explore the associations between polymorphisms in SIRT1 and coronary heart disease (CHD) risk in Chinese Han patients with type 2 diabetes (T2D).

Methods: This case-controlled study enrolled 492 patients with T2D: 297 with CHD and 195 without CHD. Five haplotype-tagging single-nucleotide polymorphisms (rs3818291, rs12242965, rs3818292, rs4746720, and rs16924934) were selected from Chinese Han data in the GRCh37.

Topoisomerase 1α is required for synchronous spermatogenesis in Physcomitrium patens.

DNA topoisomerase 1 (TOP1) plays general roles in DNA replication and transcription by regulating DNA topology in land plants and metazoans. TOP1 is also involved in specific developmental events; however, whether TOP1 plays a conserved developmental role among multicellular organisms is unknown. Here, we investigated the developmental roles of TOP1 in the moss Physcomitrium (Physcomitrella) patens with gene targeting, microscopy, 3D image segmentation and crossing experiments.

The Association of Plasma Trimethylamine N-Oxide with Coronary Atherosclerotic Burden in Patients with Type 2 Diabetes Among a Chinese North Population.

Purpose: We aimed to examine the association between plasma trimethylamine N-oxide (TMAO), a gut microbial metabolite from dietary phosphatidylcholine, and coronary atherosclerotic burden in patients with type 2 diabetes (T2D).

Methods: In total, 349 patients with T2D were studied, including 70 controls and 279 patients with coronary artery disease (CAD) by coronary angiography. Coronary atherosclerotic burden is quantified by the number of diseased coronary branches and SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery) score.

The PKCγ neurons in anterior cingulate cortex contribute to the development of neuropathic allodynia and pain-related emotion.

Background: While the PKCγ neurons in spinal dorsal horn play an indispensable part in neuropathic allodynia, the exact effect of PKCγ neurons of brain regions in neuropathic pain remains elusive. Mounting research studies have depicted that the anterior cingulate cortex (ACC) is closely linked with pain perception and behavior, the present study was designed to investigate the contribution of PKCγ neurons in ACC to neuropathic allodynia and pain-related emotion in newly developed Prkcg-P2A-Tdtomato mice.

Methods: The c-fos expression in response to innocuous stimulation was used to monitor the activity of PKCγ in CCI (chronic constriction injury of the sciatic nerve) induced neuropathic pain condition.

Pregnancy outcomes in women with type 1 diabetes in China during 2004 to 2014: A retrospective study (the CARNATION Study).

Background: We aimed to report pregnancy outcomes of women with type 1 diabetes (T1D) in China, on which data were sparse.

Methods: This is a nationwide retrospective study conducted in 11 general medical centers in 8 cities across China. We investigated the clinical data of all women who attended these centers with a singleton pregnancy and whose pregnancy ended between 1 January 2004 and 31 December 2014.

Safety-Critical Containment Maneuvering of Underactuated Autonomous Surface Vehicles Based on Neurodynamic Optimization With Control Barrier Functions.

This article addresses the safety-critical containment maneuvering of multiple underactuated autonomous surface vehicles (ASVs) in the presence of multiple stationary/moving obstacles. In a complex marine environment, every ASV suffers from model uncertainties, external disturbances, and input constraints. A safety-critical control method is proposed for achieving a collision-free containment formation.

Achieving the HbA1c Target Requires Longer Time in Range in Pregnant Women With Type 1 Diabetes.

Context: Continuous glucose monitoring (CGM) overcomes the limitations of glycated hemoglobin (HbA1c).

Objective: This study aimed to investigate the relationship between CGM metrics and laboratory HbA1c in pregnant women with type 1 diabetes.

Methods: An observational study enrolled pregnant women with type 1 diabetes who wore CGM devices during pregnancy and postpartum from 11 hospitals in China from January 2015 to June 2019.

Molecular and Electrophysiological Characterization of Dorsal Horn Neurons in a GlyT2-iCre-tdTomato Mouse Line.

Purpose: Spinal glycinergic neurons function as critical elements of a spinal gate for pain and itch. We have recently documented that spinal PKCγ neurons receive the feedforward inhibitory input driven by Aβ primary afferent. The glycinergic neurons control the excitability of PKCγ neurons and therefore gate mechanical allodynia.

Model-Free Containment Control of Underactuated Surface Vessels Under Switching Topologies Based on Guiding Vector Fields and Data-Driven Neural Predictors.

This article investigates the model-free containment control of multiple underactuated unmanned surface vessels (USVs) subject to unknown kinetic models. A novel cooperative control architecture is presented for achieving a containment formation under switching topologies. Specifically, a path-guided distributed containment motion generator (CMG) is first proposed for generating reference points according to the underlying switching topologies.