Publications by authors named "Nan Cho Nwe Mon"

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a major health concern globally. Genomic epidemiology is an important tool to assess the pandemic of coronavirus disease 2019 (COVID-19). Several mutations have been reported by genome analysis of the SARS-CoV-2.

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Background: The clinical characteristics and course of patients hospitalised with sepsis in Myanmar and the responsible pathogens remain poorly defined.

Methods: We performed an observational study of adults admitted from the community to a tertiary referral hospital in Yangon with fever and dysfunction of at least two organ systems.

Results: The 120 patients had a median age of 47 y (interquartile range 28-63); 11 (9%) were human immunodeficiency virus positive.

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Background: Plasmodium vivax malaria remains a major public health burden in Myanmar. Resistance to chloroquine (CQ), the first-line treatment for P. vivax, has been reported in the country and has potential to undermine local control efforts.

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Article Synopsis
  • The study investigated the genetic diversity of Plasmodium falciparum malaria parasites in three regions of Myanmar: two southeastern areas (Shwekyin and Myawaddy) and one western area (Kyauktaw).
  • A total of 267 blood samples from patients with acute infections were analyzed, with 184 samples successfully genotyped at three specific loci (Msp1, Msp2, and Glurp), showing significant differences in allelic distributions across the areas.
  • The findings indicated a high level of genetic diversity and a prevalence of mixed infections, with most samples exhibiting multiclonal infections and different alleles being dominant in each area, suggesting varying malaria dynamics in the regions studied.
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Background: Toxoplasma gondii, an obligate intracellular protozoan parasite, causes a disease called toxoplasmosis which can sometimes be acquired congenitally by a newborn from an infected mother. This study aimed to determine the seroprevalence of Toxoplasma infection and its associated risks among 219 and 215 pregnant women from Malaysia and Myanmar, respectively.

Methods: Anti-Toxoplasma IgG and IgM antibodies were screened by using standard commercial ELISA kits.

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