Publications by authors named "Namrata Ravi Iyengar"
Article Synopsis
- Auto-regulatory systems are essential for maintaining the optimal performance of cell processes and organelles, particularly in ensuring balance within the endoplasmic reticulum (ER).
- The study introduces a mechanism called AREX, where the protein Sec24 not only recruits cargo but also senses it and activates the signaling protein Gα12 at ER exit sites, triggering a signaling network.
- This network coordinates ER export while reducing protein synthesis to prevent harmful fluctuations in folded cargo, which may help improve our understanding of human physiology and diseases related to secretory dysfunction.
