Publications by authors named "Namrata Mawale"
We tested 65 highly pathogenic avian influenza (HPAI) A(H5N1) viruses, isolated from avian species in India between 2006 and 2015, for susceptibility to the FDA approved neuraminidase (NA) inhibitors (NAIs), oseltamivir and zanamivir using a phenotypic fluorescence-based assay. The overall incidence of resistant variants among HPAI A(H5N1) viruses was 7.69% (5/65).
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates highly pathogenic avian influenza (HPAI) H5N1 viruses in Indian poultry, particularly focusing on the clade 2.3.2.1, which has been prevalent since 2011 and differs antigenically from other clades like 2.2.
- - Researchers characterized 11 selected H5N1 viruses using antigenic cartography and phylogenetic analysis to identify differences between and within the clades, emphasizing the variability and potential implications for vaccine development.
- - The analysis included the glycosylation patterns of Hemagglutinin (HA) and growth kinetics in cell cultures, discovering that some viruses exhibit better replication, which may inform future strategies in creating effective H5 vaccine